ReviewAJNR. American journal of neuroradiology2008
Noninvasive molecular neuroimaging using reporter genes: part I, principles revisited.
Review in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Recent advances in non-invasiveBiomaterials science · 2025Review
- Advances in CAR T Cell Therapy for Non-Small Cell Lung Cancer.Current issues in molecular biology · 2023Review
- [Effects of sodium iodide symporter co-expression on proliferation and cytotoxic activity of chimeric antigen receptor T cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Radionuclide-based molecular imaging allows CAR-T cellular visualization and therapeutic monitoring.Theranostics · 2021Review
- Review
- Stem Cell Tracking Technologies for Neurological Regenerative Medicine Purposes.Stem cells international · 2017Review
- Focused ultrasound enhanced molecular imaging and gene therapy for multifusion reporter gene in glioma-bearing rat model.Oncotarget · 2015Article
- Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms.Frontiers in molecular neuroscience · 2015Review
- A Ruptured Basilar Tip Aneurysm Showing Repeated Perianeurysmal Edema after Endovascular Coil Embolization: Case Report.Neurologia medico-chirurgica · 2015Review
- A review of novel optical imaging strategies of the stroke pathology and stem cell therapy in stroke.Frontiers in cellular neuroscience · 2014Review
- Quantification of HSV-1-mediated expression of the ferritin MRI reporter in the mouse brain.Gene therapy · 2013Article
- Multimodality molecular imaging of stem cells therapy for stroke.BioMed research international · 2013Review
- Toward an integration of cognitive and genetic models of risk for depression.Cognition & emotion · 2013Review
- Bacterial vectors for imaging and cancer gene therapy: a review.Cancer gene therapy · 2012Review
- Ex vivo fluorescence molecular tomography of the spine.International journal of biomedical imaging · 2012Article
- Molecular imaging with activatable reporter systems.Theranostics · 2012Article
- Noninvasive cell-tracking methods.Nature reviews. Clinical oncology · 2011Review
- MR-based molecular imaging of the brain: the next frontier.AJNR. American journal of neuroradiology · 2010Article
- Noninvasive molecular neuroimaging using reporter genes: part II, experimental, current, and future applications.AJNR. American journal of neuroradiology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryIn this first article, we review the basic principles of using reporter genes for molecular imaging of the brain in living subjects. This approach is emerging as a valuable tool for monitoring gene expression in diverse applications in laboratory animals, including the study of gene-targeted and trafficking cells, gene therapies, transgenic animals, and more complex molecular interactions within the central nervous system. Further development of more sensitive and selective reporters, combined with improvements in detection technology, will consolidate the position of in vivo reporter gene imaging as a versatile method for greater understanding of intracellular biologic processes and underlying molecular neuropathology and will potentially establish a future role in the clinical management of patients with neurologic diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.