Evidence map›Paper›PMID 18024105›Full record

ReviewCurrent opinion in biotechnology2007

Polymers to direct cell fate by controlling the microenvironment.

R Warren Sands, David J Mooney

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  6. Review
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  12. Accelerating protein release from microparticles for regenerative medicine applications.Materials science & engineering. C, Materials for biological applications · 2013
    Article
  13. Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

R Warren SandsHarvard University, School of Engineering and Applied Sciences, Cambridge, MA 02138, USA.
David J Mooney

Funding

ENGINEERING SKELETAL MUSCLE WITH BIODEGRADABLE HYDROGELSR01DE013349 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 2000 to 2022
$9.3M
Developing Capacity to Evaluate Training Programs via Development of Human, Institutional and Social CapitalT32GM008449 · NIGMS · NORTHWESTERN UNIVERSITY · PI LEONARD, JOSHUA NATHANIEL · 1993 to 2023
$7.8M
Engineering Capillary NetworksR01HL069957 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 2003 to 2013
$4.2M
Polymeric Matrices with Defined Cell AdhesionR37DE013033 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOONEY, DAVID J · 2004 to 2013
$3.8M
NHLBI NIH HHS R01 HL069957NIDCR NIH HHS R01 DE013349NIDCR NIH HHS R37 DE013033NIGMS NIH HHS 5 T32 GM008449-13
6 · The paper itself

Abstract

Enhanced understanding of the signals within the microenvironment that regulate cell fate has led to the development of increasingly sophisticated polymeric biomaterials for tissue engineering and regenerative medicine applications. This advancement is exemplified by biomaterials with precisely controlled scaffold architecture that regulate the spatio-temporal release of growth factors and morphogens, and respond dynamically to microenvironmental cues. Further understanding of the biology, qualitatively and quantitatively, of cells within their microenvironments and at the tissue-material interface will expand the design space of future biomaterials.

Indexed as

Cell Physiological PhenomenaBiocompatible MaterialsCell Culture TechniquesCell TransplantationPolymersRegenerative MedicineTissue EngineeringBiocompatible MaterialsPolymers

Identifiers

PMID18024105
PMCPMC2262952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.