Evidence map›Paper›PMID 18023633›Full record

ReviewCellular immunology2007

Allopeptides and the alloimmune response.

Ankit Bharat, T Mohanakumar

Abstract readReview
In one paragraph

Review in Cellular immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Alloimmunity and autoimmunity in chronic rejection.Current opinion in organ transplantation · 2010
    Review
  15. New concepts in alloimmune recognition.Cellular immunology · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ankit BharatDepartment of Surgery, Washington University School of Medicine, Box 8109-3328 CSRB, 660 S. Euclid Avenue, St. Louis, MO 63110, USA. bharata@wudosis.wustl.edu
T Mohanakumar

Funding

IMMUNE MECHANISMS OF REJECTION IN HUMAN LUNG ALLOGRAFTSR01HL056643 · NHLBI · WASHINGTON UNIVERSITY · PI MOHANAKUMAR, THALACHALLOUR · 1996 to 2015
$6.5M
PATHOGENESIS OF POST-TRANSPLANT BRONCHIOLITIS OBLITERANSR01HL066452 · NHLBI · WASHINGTON UNIVERSITY · PI MOHANAKUMAR, THALACHALLOUR · 2001 to 2004
$1.2M
Pathogenesis of Post-Transplant Bronchiolitis ObliteransR56HL066452 · NHLBI · WASHINGTON UNIVERSITY · PI MOHANAKUMAR, THALACHALLOUR · 2008 to 2008
$380k
VERSATILE MULTIWAVELENGTH FLUOROMETERR43HL056543 · NHLBI · C AND L INSTRUMENTS, INC. · PI WANG, LI · 1995 to 1995
–
VERSATILE MULTIWAVELENGTH FLUOROMETERR44HL056543 · NHLBI · C AND L INSTRUMENTS, INC. · PI XIA, WEISHAN R · 1997 to 1998
–
NHLBI NIH HHS HL 56543NHLBI NIH HHS HL66452NHLBI NIH HHS R01 HL056643NHLBI NIH HHS R01 HL066452NHLBI NIH HHS R56 HL066452
6 · The paper itself

Abstract

The inherent ability of the host immune system to distinguish between self- and non-self forms the basis of allorecognition. T lymphocytes constitute the most important effector arm of allorecognition. Here we describe the fundamentals of direct and indirect pathways by which allopeptides are presented to effector T cells. The nature of allopeptides presented along with tolerogenic strategies like altered peptide ligands and intra- or extra-thymic allopeptide inoculation are discussed. In addition, we speculate on the potential of regulatory T cells to modulate alloimmune responses.

Indexed as

Antigen PresentationImmune ToleranceAnimalsGraft RejectionGraft SurvivalHeart TransplantationHistocompatibility AntigensHumansImmunosuppressive AgentsIsoantigensKidney TransplantationLymphocyte ActivationMiceModels, AnimalPeptidesRatsHistocompatibility AntigensImmunosuppressive AgentsIsoantigensPeptides

Identifiers

PMID18023633
PMCPMC2170891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.