Evidence map›Paper›PMID 18008096›Full record

ArticleDocumenta ophthalmologica. Advances in ophthalmology2008

Annular fundus autofluorescence abnormality in a case of macular dystrophy.

Charlotte M Poloschek, Lutz L Hansen, Michael Bach

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In one paragraph

Article in Documenta ophthalmologica. Advances in ophthalmology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. [Imaging and molecular genetic diagnostics for the characterization of retinal dystrophies].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2018
    Review
  2. Article
  3. Imaging and the perspective of clinical electrophysiology.Documenta ophthalmologica. Advances in ophthalmology · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Charlotte M PoloschekDepartment of Ophthalmology, University of Freiburg, Killianstr. 5, 79106 Freiburg, Germany. charlotte.poloschek@uniklinik-freiburg.de
Lutz L Hansen
Michael Bach
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present a case of macular dystrophy with early changes in fundus autofluorescence.

methodsA 20-year-old woman with a recent loss of visual acuity and onset of photophobia was examined. Color vision and visual field testing, fluorescein angiography, full-field and multifocal electroretinograms as well as fundus autofluorescence were performed.

resultsBest-corrected visual acuity was 20/100 (right eye) and 20/60 (left eye). There was a red-green color vision defect and a relative central scotoma in both eyes. Ophthalmoscopy and fluorescein angiography were essentially normal, the presence of a dark choroid was debatable. Full-field ERG responses were normal, but the multifocal ERG showed severely reduced responses in the macular region. Both eyes showed a slight circular parafoveolar increase of fundus autofluorescence.

conclusionBesides multifocal ERG, fundus autofluorescence aids to objectively assess the manifestation of macular dystrophies but does not discern between different types in early stages.

Indexed as

ElectroretinographyFluorescenceFundus OculiAdultColor Perception TestsFemaleFluorescein AngiographyHumansMacular DegenerationOphthalmoscopyVisual AcuityVisual Fields

Identifiers

PMID18008096
OpenAlexW2043258940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.