Evidence map›Paper›PMID 18008037›Full record

ArticleJournal of gastroenterology2007

Clinical potential of an antitumor drug sensitivity test and diffusion-weighted MRI in a patient with a recurrent solid pseudopapillary tumor of the pancreas.

Tomoharu Shimizu, Satoshi Murata, Eiji Mekata, Tohru Miyake, Hajime Abe, Yoshimasa Kurumi, Yoshihiro Endo, Ryoji Kushima, Tohru Tani

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PubMed Publisher
In one paragraph

Article in Journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  6. A rare case of primary choriocarcinoma in the sigmoid colon.World journal of gastroenterology · 2013
    Article
  7. Clinical predictive value ofMolecular and clinical oncology · 2013
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tomoharu ShimizuDepartment of Surgery, Shiga University of Medical Science, Seta-tsukinowa, Otsu 520-2192, Japan.
Satoshi Murata
Eiji Mekata
Tohru Miyake
Hajime Abe
Yoshimasa Kurumi
Yoshihiro Endo
Ryoji Kushima
Tohru Tani
Shiga University of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A solid pseudopapillary tumor (SPT) of the pancreas is a rare type of pancreatic neoplasm found predominantly in young women. SPTs typically behave as though benign; however, in some cases they also have malignant potential. We encountered a rare case of a recurrent SPT that developed 4 years after the initial surgery in an elderly male patient. Abdominal computed tomography (CT) revealed that the 61-year-old patient had four intra-abdominal masses, suggesting a recurrence of SPT. The patient had a history of distal pancreatectomy due to SPT in the pancreatic tail 4 years previously. These tumors showed positive signals on diffusion-weighted magnetic resonance imaging (MRI), and were treated successfully by aggressive surgical resection. Microscopic diagnosis was compatible with recurrent tumors of SPT. A chemosensitivity test, the collagen gel droplet-embedded culture drug sensitivity test (CD-DST), showed that the resected tumors were sensitive to several antitumor drugs. We suggest that the CD-DST may be used to indicate promising antitumor agents for treating SPTs with malignant tendencies. In addition, a diffusion-weighted MRI can be useful for accurately visualizing SPTs of the pancreas.

Indexed as

Antimetabolites, AntineoplasticCarcinoma, PapillaryDeoxycytidineDiffusion Magnetic Resonance ImagingDrug Screening Assays, AntitumorGemcitabineHumansMaleMiddle AgedPancreatic NeoplasmsRadiographyAntimetabolites, AntineoplasticDeoxycytidineGemcitabine

Identifiers

PMID18008037
OpenAlexW2044458845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.