Evidence map›Paper›PMID 18006570›Full record

ArticleNucleic acids research2008

ORegAnno: an open-access community-driven resource for regulatory annotation.

Obi L Griffith, Stephen B Montgomery, Bridget Bernier, Bryan Chu, Katayoon Kasaian, Stein Aerts, Shaun Mahony, Monica C Sleumer, Mikhail Bilenky, Maximilian Haeussler and 20 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 146 papers.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

146 citing papers in PubMed.

  1. Article
  2. Association ofReports of biochemistry & molecular biology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Role ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Eric Davidson's Regulatory Genome for Computer Science: Causality, Logic, and Proof Principles of the GenomicJournal of computational biology : a journal of computational molecular cell biology · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Obi L GriffithCanada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada. obig@bcgsc.ca
Stephen B Montgomery
Bridget Bernier
Bryan Chu
Katayoon Kasaian
Stein Aerts
Shaun Mahony
Monica C Sleumer
Mikhail Bilenky
Maximilian Haeussler
Malachi Griffith
Steven M Gallo
Belinda Giardine
Bart Hooghe
Peter Van Loo
Enrique Blanco
Amy Ticoll
Stuart Lithwick
Elodie Portales-Casamar
Ian J Donaldson
Gordon Robertson
Claes Wadelius
Pieter De Bleser
Dominique Vlieghe
Marc S Halfon
Wyeth Wasserman
Ross Hardison
Casey M Bergman
Steven J M Jones
Open Regulatory Annotation Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ORegAnno is an open-source, open-access database and literature curation system for community-based annotation of experimentally identified DNA regulatory regions, transcription factor binding sites and regulatory variants. The current release comprises 30 145 records curated from 922 publications and describing regulatory sequences for over 3853 genes and 465 transcription factors from 19 species. A new feature called the 'publication queue' allows users to input relevant papers from scientific literature as targets for annotation. The queue contains 4438 gene regulation papers entered by experts and another 54 351 identified by text-mining methods. Users can enter or 'check out' papers from the queue for manual curation using a series of user-friendly annotation pages. A typical record entry consists of species, sequence type, sequence, target gene, binding factor, experimental outcome and one or more lines of experimental evidence. An evidence ontology was developed to describe and categorize these experiments. Records are cross-referenced to Ensembl or Entrez gene identifiers, PubMed and dbSNP and can be visualized in the Ensembl or UCSC genome browsers. All data are freely available through search pages, XML data dumps or web services at: http://www.oreganno.org.

Indexed as

Databases, Nucleic AcidRegulatory Elements, TranscriptionalAccess to InformationAnimalsBinding SitesHumansInternetTranscription FactorsUser-Computer InterfaceTranscription Factors

Identifiers

PMID18006570
PMCPMC2239002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.