ArticleCell host & microbe2007
The complex relationship between mycobacteria and macrophages: it's not all bliss.
Article in Cell host & microbe, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Drug permeation and metabolism in Mycobacterium tuberculosis: Prioritising local exposure as essential criterion in new TB drug development.IUBMB life · 2018Review
- Review
- Mycobacterial escape from macrophage phagosomes to the cytoplasm represents an alternate adaptation mechanism.Scientific reports · 2016Article
- Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo.PLoS pathogens · 2015Article
- Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens.PLoS pathogens · 2012Article
- Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.PLoS pathogens · 2012Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycobacteria are uniquely adapted to grow inside host macrophages. As Clay et al. show in this issue of Cell Host & Microbe and as van der Wel et al. show in a recent issue of Cell, there are both benefits and drawbacks for the pathogen in adopting this strategy, and some of our fundamental assumptions about how the host cell and bacterium interact might need to be reexamined.
Indexed as
Identifiers
18005712What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.