ArticleBMC biology2007
Adaptive sequence evolution in a color gene involved in the formation of the characteristic egg-dummies of male haplochromine cichlid fishes.
Article in BMC biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed, 104 citations in OpenAlex.
- Article
- Neural crest cells as a source of microevolutionary variation.Seminars in cell & developmental biology · 2023Review
- East African cichlid fishes.EvoDevo · 2023Review
- Phylogenomics of trophically diverse cichlids disentangles processes driving adaptive radiation and repeated trophic transitions.Ecology and evolution · 2022Article
- Gene expression in male and female stickleback from populations with convergent and divergent throat coloration.Ecology and evolution · 2022Article
- Genetic basis of orange spot formation in the guppy (Poecilia reticulata).BMC ecology and evolution · 2021Article
- Carotenoid coloration and coloration-linked gene expression in red tilapia (Oreochromis sp.) tissues.BMC veterinary research · 2021Article
- Spiny and soft-rayed fin domains in acanthomorph fish are established through a BMP-Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Genetic architecture underlying changes in carotenoid accumulation during the evolution of the blind Mexican cavefish, Astyanax mexicanus.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2020Article
- New haplochromine cichlid from the upper Miocene (9-10 MYA) of Central Kenya.BMC evolutionary biology · 2020Article
- Unique and non-redundant function ofDevelopment (Cambridge, England) · 2020Article
- Red carotenoids and associated gene expression explain colour variation in frillneck lizards.Proceedings. Biological sciences · 2019Article
- Variations in the breeding behavior of cichlids and the evolution of the multi-functional seminal plasma protein, seminal plasma glycoprotein 120.BMC evolutionary biology · 2018Article
- Phylogenomics uncovers early hybridization and adaptive loci shaping the radiation of Lake Tanganyika cichlid fishes.Nature communications · 2018Article
- The Colorful Sex Chromosomes of Teleost Fish.Genes · 2018Review
- The skeletal ontogeny of Astatotilapia burtoni - a direct-developing model system for the evolution and development of the teleost body plan.BMC developmental biology · 2018Article
- Article
- Incipient sympatric speciation in Midas cichlid fish from the youngest and one of the smallest crater lakes in Nicaragua due to differential use of the benthic and limnetic habitats?Ecology and evolution · 2016Article
- Are sympatrically speciating Midas cichlid fish special? Patterns of morphological and genetic variation in the closely related species Archocentrus centrarchus.Ecology and evolution · 2016Article
- The Asian arowana (Scleropages formosus) genome provides new insights into the evolution of an early lineage of teleosts.Scientific reports · 2016Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe exceptionally diverse species flocks of cichlid fishes in East Africa are prime examples of parallel adaptive radiations. About 80% of East Africa's more than 1 800 endemic cichlid species, and all species of the flocks of Lakes Victoria and Malawi, belong to a particularly rapidly evolving lineage, the haplochromines. One characteristic feature of the haplochromines is their possession of egg-dummies on the males' anal fins. These egg-spots mimic real eggs and play an important role in the mating system of these maternal mouthbrooding fish.
resultsHere, we show that the egg-spots of haplochromines are made up of yellow pigment cells, xanthophores, and that a gene coding for a type III receptor tyrosine kinase, colony-stimulating factor 1 receptor a (csf1ra), is expressed in egg-spot tissue. Molecular evolutionary analyses reveal that the extracellular ligand-binding and receptor-interacting domain of csf1ra underwent adaptive sequence evolution in the ancestral lineage of the haplochromines, coinciding with the emergence of egg-dummies. We also find that csf1ra is expressed in the egg-dummies of a distantly related cichlid species, the ectodine cichlid Ophthalmotilapia ventralis, in which markings with similar functions evolved on the pelvic fin in convergence to those of the haplochromines.
conclusionWe conclude that modifications of existing signal transduction mechanisms might have evolved in the haplochromine lineage in association with the origination of anal fin egg-dummies. That positive selection has acted during the evolution of a color gene that seems to be involved in the morphogenesis of a sexually selected trait, the egg-dummies, highlights the importance of further investigations of the comparative genomic basis of the phenotypic diversification of cichlid fishes.
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