ArticleInvertebrate neuroscience : IN2008
Study of nicotinic acetylcholine receptors on cultured antennal lobe neurones from adult honeybee brains.
Article in Invertebrate neuroscience : IN, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 83 citations in OpenAlex.
- Functional expression and properties of the tick α6 homomeric nicotinic acetylcholine receptor inCurrent research in parasitology & vector-borne diseases · 2025Article
- Article
- Acetylcholine and choline in honey bee (Apis mellifera) worker brood food are seasonal and age-dependent.Scientific reports · 2024Article
- Cardiotoxicity of the diamide insecticide chlorantraniliprole in the intact heart and in isolated cardiomyocytes from the honey bee.Scientific reports · 2024Article
- Critical roles of nicotinic acetylcholine receptors in olfactory memory formation and retrieval in crickets.Frontiers in physiology · 2024Article
- The Power ofFrontiers in physiology · 2021Review
- Acute Application of Imidacloprid Alters the Sensitivity of Direction Selective Motion Detecting Neurons in an Insect Pollinator.Frontiers in physiology · 2021Article
- Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Imidacloprid impairs performance on a model flower handling task in bumblebees (Bombus impatiens).Ecotoxicology (London, England) · 2020Article
- Honeybees fail to discriminate floral scents in a complex learning task after consuming a neonicotinoid pesticide.The Journal of experimental biology · 2020Article
- Cell Lines for Honey Bee Virus Research.Viruses · 2020Review
- Bee Viruses: Routes of Infection in Hymenoptera.Frontiers in microbiology · 2020Review
- Cloning and Expression of Cockroach α7 Nicotinic Acetylcholine Receptor Subunit.Frontiers in physiology · 2020Article
- Acetylcholine and Its Receptors in Honeybees: Involvement in Development and Impairments by Neonicotinoids.Insects · 2019Review
- The Neurophysiological Bases of the Impact of Neonicotinoid Pesticides on the Behaviour of Honeybees.Insects · 2019Review
- Imidacloprid slows the development of preference for rewarding food sources in bumblebees (Bombus impatiens).Ecotoxicology (London, England) · 2018Article
- Neonicotinoid-induced impairment of odour coding in the honeybee.Scientific reports · 2016Article
- Antiviral Defense Mechanisms in Honey Bees.Current opinion in insect science · 2015Article
- A Locomotor Deficit Induced by Sublethal Doses of Pyrethroid and Neonicotinoid Insecticides in the Honeybee Apis mellifera.PloS one · 2015Article
- RNAi and Antiviral Defense in the Honey Bee.Journal of immunology research · 2015Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In insects, acetylcholine (ACh) is the main neurotransmitter, and nicotinic acetylcholine receptors (nAChRs) mediate fast cholinergic synaptic transmission. In the honeybee, nAChRs are expressed in diverse structures including the primary olfactory centres of the brain, the antennal lobes (AL) and the mushroom bodies. Whole-cell, voltage-clamp recordings were used to characterize the nAChRs present on cultured AL cells from adult honeybee, Apis mellifera. In 90% of the cells, applications of ACh induced fast inward currents that desensitized slowly. The classical nicotinic agonists nicotine and imidacloprid elicited respectively 45 and 43% of the maximum ACh-induced currents. The ACh-elicited currents were blocked by nicotinic antagonists methyllycaconitine, dihydroxy-beta-erythroidine and alpha-bungarotoxin. The nAChRs on adult AL cells are cation permeable channels. Our data indicate the existence of functional nAChRs on adult AL cells that differ from nAChRs on pupal Kenyon cells from mushroom bodies by their pharmacological profile and ionic permeability, suggesting that these receptors could be implicated in different functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.