Evidence map›Paper›PMID 18003906›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2007

The process of mRNA-tRNA translocation.

Joachim Frank, Haixiao Gao, Jayati Sengupta, Ning Gao, Derek J Taylor

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed.

  1. Perspective - RNA Dynamics Today and Tomorrow.Journal of molecular biology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Bio-protocol · 2022
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. New Insights into Ribosome Structure and Function.Cold Spring Harbor perspectives in biology · 2019
    Review
  16. Review
  17. Ribosome Structure, Function, and Early Evolution.International journal of molecular sciences · 2018
    Review
  18. Article
  19. Review
  20. Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joachim FrankHoward Hughes Medical Institute and Health Research Incorporated, Wadsworth Center, Empire State Plaza, Albany, NY 12201-0509, USA. joachim@wadsworth.org
Haixiao Gao
Jayati Sengupta
Ning Gao
Derek J Taylor

Funding

ZERNIKE PHASE-CONTRAST IMAGINGP41RR001219 · NCRR · WADSWORTH CENTER · PI MANNELLA, CARMEN A. · 1985 to 2010
$11.1M
Time-resolved Cryo-EM of Short-lived States in Eukaryotic TranslationR01GM055440 · NIGMS · WADSWORTH CENTER · PI FRANK, JOACHIM · 1997 to 2020
$5.1M
STRUCTURAL ANALYSIS OF MACROMOLECULAR ASSEMBLYR37GM029169 · NIGMS · WADSWORTH CENTER · PI FRANK, JOACHIM · 1997 to 2006
$2.8M
NCRR NIH HHS P41 RR001219NCRR NIH HHS P41 RR01219NIGMS NIH HHS R01 GM055440NIGMS NIH HHS R01 GM55440NIGMS NIH HHS R37 GM029169NIGMS NIH HHS R37 GM29169
6 · The paper itself

Abstract

In the elongation cycle of translation, translocation is the process that advances the mRNA-tRNA moiety on the ribosome, to allow the next codon to move into the decoding center. New results obtained by cryoelectron microscopy, interpreted in the light of x-ray structures and kinetic data, allow us to develop a model of the molecular events during translocation.

Indexed as

AnimalsBiological TransportCatalysisGuanosine TriphosphateHumansHydrolysisModels, GeneticPeptide Elongation Factor GRibosomesRNA, MessengerRNA, TransferGuanosine TriphosphatePeptide Elongation Factor GRNA, MessengerRNA, Transfer

Identifiers

PMID18003906
PMCPMC2148355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.