Evidence map›Paper›PMID 18003800›Full record

ArticleJournal of clinical microbiology2008

Fungal infection in patients with serpiginous choroiditis or acute zonal occult outer retinopathy.

Diana Pisa, Marta Ramos, Patricia García, Remberto Escoto, Rafael Barraquer, Susana Molina, Luis Carrasco

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Tubercular serpiginous choroiditis.Journal of ophthalmic inflammation and infection · 2022
    Review
  4. Occurrence ofGerms · 2020
    Article
  5. Enigma of serpiginous choroiditis.Indian journal of ophthalmology · 2019
    Review
  6. Article
  7. Article
  8. [Arch-shaped retinal appearance of a previously healthy women].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Alzheimer's disease and disseminated mycoses.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
  13. Fungal infection in cerebrospinal fluid from some patients with multiple sclerosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013
    Article
  14. Fungal infection in a patient with multiple sclerosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011
    Article
  15. Association between multiple sclerosis and Candida species: evidence from a case-control study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Diana PisaCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Facultad de Ciencias, Universidad Autónoma, Cantoblanco, 28049 Madrid, Spain.
Marta Ramos
Patricia García
Remberto Escoto
Rafael Barraquer
Susana Molina
Luis Carrasco
Centro de Biología Molecular Severo Ochoa · ESBarraquer Opthalmology Center · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The etiologies of a number of retinopathies, including serpiginous choroiditis and acute zonal occult outer retinopathy (AZOOR), remain uncertain. Recently, we provided evidence that AZOOR is caused by Candida famata infection. The purpose of this article was to investigate the presence of fungal infection in five patients affected with serpiginous choroiditis and five patients with diagnosis of AZOOR. To assess the presence of fungal infection the presence of antibodies in human serum samples against C. famata, C. albicans, C. parapsilosis, C. glabrata and C. krusei was analyzed. In addition, quantitative PCR was carried out to detect fungal genomes in whole blood. Finally, the presence of fungal antigens in the serum samples of patients was investigated. Three AZOOR patients presented high antibody titers against Candida spp., while antibodies against Candida spp. were observed in serum samples from four patients with serpiginous choroiditis. Fungal genomes in peripheral blood were evidenced in serum samples from one AZOOR and four serpiginous choroiditis patients. Fungal antigens were also apparent in the serum of different patients. Our findings indicate that there was evidence of disseminated fungal infection in most patients examined.

Indexed as

AdolescentAdultAgedAnimalsAntibodies, FungalCandidaCandidiasisChoroiditisDNA, FungalFemaleFluorescent Antibody Technique, IndirectHumansMaleMiddle AgedPolymerase Chain ReactionRabbitsAntibodies, FungalDNA, Fungal

Identifiers

PMID18003800
PMCPMC2224286
OpenAlexW1984499405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.