Evidence map›Paper›PMID 18003799›Full record

ArticleJournal of clinical microbiology2008

Evaluation of a Chlamydophila psittaci infection diagnostic platform for zoonotic risk assessment.

Kristel Verminnen, Barbara Duquenne, David De Keukeleire, Birgitta Duim, Yvonne Pannekoek, Lutgart Braeckman, Daisy Vanrompay

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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  15. Avian chlamydiophilosis in a Manitoba farmed pigeon flock.The Canadian veterinary journal = La revue veterinaire canadienne · 2010
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kristel VerminnenDepartment of Molecular Biotechnology, FBW-Ghent University, Coupure Links 653, B-9000 Ghent, Belgium. Kristel.Verminnen@UGent.be
Barbara Duquenne
David De Keukeleire
Birgitta Duim
Yvonne Pannekoek
Lutgart Braeckman
Daisy Vanrompay
Ghent University · BEUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports on zoonotic transmission of Chlamydophila psittaci originating from poultry are incidentally published. During recent studies in European turkeys we isolated C. psittaci genotypes A, B, D, E, F, and E/B, all considered potentially dangerous for humans. This encouraged us to analyze the zoonotic risk on a Belgian turkey farm, from production onset until slaughter, using a Chlamydophila psittaci diagnostic platform. Twenty individually marked hens, as well as the farmer and two scientists, were monitored medically. Bioaerosol monitoring, serology, isolation, and nested PCR demonstrated chlamydiosis on the farm leading to symptomatic psittacosis in all 3 persons involved. ompA sequencing confirmed the zoonotic transmission of C. psittaci genotype A. Strangely, two different antibody microimmunofluorescence (MIF) tests remained negative in all infected persons. The results demonstrate the value of the currently used diagnostic platform in demonstrating C. psittaci infections in both birds and humans but raise questions regarding use of the MIF test for diagnosing human psittacosis. In addition, our results suggest the underestimation of psittacosis in the poultry industry, stressing the need for a veterinary vaccine and recommendations for zoonotic risk reduction strategies.

Indexed as

AnimalsBacterial Outer Membrane ProteinsBacterial Typing TechniquesBelgiumBird DiseasesChlamydophila psittaciFemaleFluorescent Antibody TechniqueGenotypeHumansMalePolymerase Chain ReactionPoultry DiseasesPsittacosisRisk AssessmentSequence Analysis, DNABacterial Outer Membrane ProteinsOMPA outer membrane proteins

Identifiers

PMID18003799
PMCPMC2224303
OpenAlexW2148540932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.