ArticleMolecular microbiology2007
Cell-specific SpoIIIE assembly and DNA translocation polarity are dictated by chromosome orientation.
Article in Molecular microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Type IV secretion systems: reconciling diversity through a unified nomenclature.FEMS microbiology reviews · 2026Review
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- Metabolic differentiation and intercellular nurturing underpin bacterial endospore formation.Science advances · 2021Article
- Milestones inMicrobial cell (Graz, Austria) · 2020Review
- Shaping an Endospore: Architectural Transformations DuringAnnual review of microbiology · 2020Review
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- Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis.PloS one · 2018Article
- Polar Organizing Protein PopZ Is Required for Chromosome Segregation in Agrobacterium tumefaciens.Journal of bacteriology · 2017Article
- Kinetics of large-scale chromosomal movement during asymmetric cell division in Escherichia coli.PLoS genetics · 2017Article
- Phosphorylation of spore coat proteins by a family of atypical protein kinases.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- A Novel Cell Type EnablesFrontiers in microbiology · 2016Article
- Visualization and functional dissection of coaxial paired SpoIIIE channels across the sporulation septum.eLife · 2015Article
- Mechanistic study of classical translocation-dead SpoIIIE36 reveals the functional importance of the hinge within the SpoIIIE motor.Journal of bacteriology · 2014Article
- Spore formation in Bacillus subtilis.Environmental microbiology reports · 2014Review
- SpoIIIE protein achieves directional DNA translocation through allosteric regulation of ATPase activity by an accessory domain.The Journal of biological chemistry · 2013Article
- The SpoIIQ landmark protein has different requirements for septal localization and immobilization.Molecular microbiology · 2013Article
- Peptidoglycan transformations during Bacillus subtilis sporulation.Molecular microbiology · 2013Article
- Article
- Chromosome architecture is a key element of bacterial cellular organization.Cellular microbiology · 2013Review
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Abstract
SpoIIIE and FtsK are related proteins that translocate chromosomes across septa. Previous results suggested that SpoIIIE exports DNA and that translocation polarity is governed by the cell-specific regulation of its assembly, but that FtsK is a reversible motor for which translocation polarity is governed by its DNA substrate. Seeking to reconcile these conclusions, we used cell-specific GFP tagging to demonstrate that SpoIIIE assembles a complex only in the mother cell, from which DNA is exported, but that DNA translocation-defective SpoIIIE proteins assemble in both cells. Altering chromosome architecture by soj-spo0J and racA soj-spo0J mutations allowed wild-type SpoIIIE to assemble in the forespore and export the forespore chromosome. Combining LacI-CFP tagging of oriC with time-lapse microscopy, we demonstrate that the chromosome is exported from the forespore when oriC fails to be trapped in the forespore. Thus, the position of oriC after septation determines which cell will receive the chromosome and which will assemble SpoIIIE.
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