Evidence map›Paper›PMID 18000133›Full record

ArticleJournal of epidemiology and community health2007

Use of statins and beta-blockers after acute myocardial infarction according to income and education.

Jeppe N Rasmussen, Gunnar H Gislason, Søren Rasmussen, Steen Z Abildstrom, Tina K Schramm, Lars Køber, Finn Diderichsen, Merete Osler, Christian Torp-Pedersen, Mette Madsen

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Myocardial infarction care in low and high socioeconomic environments: claims data analysis.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of Socioeconomic Factors and Gender on Refill Adherence and Persistence to Lipid-Lowering Therapy in Type 1 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Article
  9. Article
  10. Disparities in Statin Use in New York City: Implications for Health Reform.Journal of racial and ethnic health disparities · 2019
    Article
  11. Article
  12. Improving long-term adherence to statin therapy: a qualitative study of GPs' experiences in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Jeppe N RasmussenNational Institute of Public Health, Øster Farimagsgade 5, DK-1399 Copenhagen K, Denmark. jnr@niph.dk
Gunnar H Gislason
Søren Rasmussen
Steen Z Abildstrom
Tina K Schramm
Lars Køber
Finn Diderichsen
Merete Osler
Christian Torp-Pedersen
Mette Madsen
Danish National Institute of Public Health · DKBispebjerg Hospital · DKGentofte Hospital · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the initiation of and long-term refill persistency with statins and beta-blockers after acute myocardial infarction (AMI) according to income and education. DESIGN AND

settingLinkage of individuals through national registers of hospitalisations, drug dispensation, income and education.

participants30 078 patients aged 30-74 years surviving first hospitalisation for AMI in Denmark between 1995 and 2001.

main outcome measuresInitiation of statin or beta-blocker treatment (out-patient claim of prescriptions within 6 months of discharge) and refill persistency (first break in treatment lasting at least 90 days, and re-initiation of treatment after a break).

resultsWhen simultaneously estimating the effect of income and education on initiation of treatment, the effect of education attenuated and a clear income gradient remained for both drugs. Among patients aged 30-64 years, high income (adjusted hazard ratio (HR) 1.27; 95% confidence interval (CI) 1.19-1.35) and medium income (HR 1.13; 95% CI 1.06-1.20) was associated with initiation of statin treatment compared with low income. The risk of break in statin treatment was lower for patients with high (HR 0.73; 95% CI 0.66-0.82) and medium (HR 0.82; 95% CI 0.74-0.92) income compared with low income, whereas there was a trend in the opposite direction concerning a break in beta-blocker treatment. There was no gradient in re-initiation of treatment.

conclusionPatients with low compared with high income less frequently initiated preventive treatment post-AMI, had worse long-term persistency with statins, but tended to have better persistency with beta-blockers. Low income by itself seems not to be associated with poor long-term refill persistency post-AMI.

Indexed as

Patient ComplianceAdrenergic beta-AntagonistsAdultAgedConfidence IntervalsDenmarkDrug CostsEducational StatusFemaleHealth SurveysHospitalizationHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIncomeMaleMiddle AgedAdrenergic beta-AntagonistsHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID18000133
PMCPMC2465659
OpenAlexW2168782458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.