SynthesisJournal of epidemiology and community health2007
Systematic review of the fetal effects of prenatal binge-drinking.
Synthesis in Journal of epidemiology and community health, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 180 citations in OpenAlex.
- Does parental drinking influence children's drinking? A systematic review of prospective cohort studies.Addiction (Abingdon, England) · 2016Pooled it
- Pooled it
- Dose-response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)-a systematic review and meta-analyses.BJOG : an international journal of obstetrics and gynaecology · 2011Pooled it
- The association of maternal alcohol use and paraprofessional home visiting with children's health: A randomized controlled trial.Journal of consulting and clinical psychology · 2019Trial
- Trial
- Adherence to Healthy Prepregnancy Lifestyle and Risk of Adverse Pregnancy Outcomes: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Barriers and enablers to addressing smoking, nutrition, alcohol consumption, physical activity and gestational weight gain (SNAP-W) as part of antenatal care: A mixed methods systematic review.Implementation science communications · 2024Review
- Improving the quality of antenatal screening and early intervention for alcohol and other drug use: protocol for a multi-stage approach to systems reform.Addiction science & clinical practice · 2024Article
- In Utero Exposure to Alcohol and Tobacco and Electroencephalogram Power During Childhood.JAMA network open · 2024Article
- Metabolic risk factors and fertility disorders: A narrative review of the female perspective.Reproductive biomedicine & society online · 2022Review
- Cholinergic and Neuroimmune Signaling Interact to Impact Adult Hippocampal Neurogenesis and Alcohol Pathology Across Development.Frontiers in pharmacology · 2022Review
- Lifestyle Habits among Pregnant Women in Denmark during the First COVID-19 Lockdown Compared with a Historical Period-A Hospital-Based Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- [Binge drinking: the challenges of definition and its impact on health.]Revista espanola de salud publica · 2020Article
- Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids.Translational psychiatry · 2020Article
- Implementation strategies to improve preconception and antenatal care for tobacco smoking, alcohol consumption and weight management: a systematic review protocol.Systematic reviews · 2019Article
- Alcohol use and associated factors among women attending antenatal care in Southern Ethiopia: a facility based cross sectional study.BMC research notes · 2019Article
- Pregnant Women's Risk Perception of the Teratogenic Effects of Alcohol Consumption in Pregnancy.Journal of clinical medicine · 2019Article
- Perceptions of Alcohol Advertising Vary Based on Psychological Characteristics.Substance use & misuse · 2019Article
- Warning about drinking during pregnancy: lessons from the French experience.Reproductive health · 2018Article
- The Early Developmental Outcomes of Prenatal Alcohol Exposure: A Review.Frontiers in neurology · 2018Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe effects of binge-drinking during pregnancy on the fetus and child have been an increasing concern for clinicians and policy-makers. This study reviews the available evidence from human observational studies.
designSystematic review of observational studies. POPULATION: Pregnant women or women who are trying to become pregnant.
methodsA computerised search strategy was run in Medline, Embase, Cinahl and PsychInfo for the years 1970-2005. Titles and abstracts were read by two researchers for eligibility. Eligible papers were then obtained and read in full by two researchers to decide on inclusion. The papers were assessed for quality using the Newcastle-Ottawa Quality Assessment Scales and data were extracted.
main outcome measuresAdverse outcomes considered in this study included miscarriage; stillbirth; intrauterine growth restriction; prematurity; birth-weight; small for gestational age at birth; and birth defects, including fetal alcohol syndrome and neurodevelopmental effects.
resultsThe search resulted in 3630 titles and abstracts, which were narrowed down to 14 relevant papers. There were no consistently significant effects of alcohol on any of the outcomes considered. There was a possible effect on neurodevelopment. Many of the reported studies had methodological weaknesses despite being assessed as having reasonable quality.
conclusionsThis systematic review found no convincing evidence of adverse effects of prenatal binge-drinking, except possibly on neurodevelopmental outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.