Evidence map›Paper›PMID 18000002›Full record

ArticleNucleic acids research2008

The BioGRID Interaction Database: 2008 update.

Bobby-Joe Breitkreutz, Chris Stark, Teresa Reguly, Lorrie Boucher, Ashton Breitkreutz, Michael Livstone, Rose Oughtred, Daniel H Lackner, Jürg Bähler, Valerie Wood and 2 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 337 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
337citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

337 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Pathway-guided architectures for interpretable AI in biological research.Computational and structural biotechnology journal · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Biological network analysis with deep learning.Briefings in bioinformatics · 2021
    Review
  19. Article
  20. Article

277 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bobby-Joe BreitkreutzSamuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada.
Chris Stark
Teresa Reguly
Lorrie Boucher
Ashton Breitkreutz
Michael Livstone
Rose Oughtred
Daniel H Lackner
Jürg Bähler
Valerie Wood
Kara Dolinski
Mike Tyers

Funding

BioGRID: an open resource for biological interactions and network analysisR01RR024031 · NCRR · SINAI HEALTH SYSTEM · PI TYERS, MIKE · 2007 to 2011
$3.2M
Cancer Research UK A6517NCRR NIH HHS 1R01RR024031-01NCRR NIH HHS R01 RR024031Wellcome Trust 077118
6 · The paper itself

Abstract

The Biological General Repository for Interaction Datasets (BioGRID) database (http://www.thebiogrid.org) was developed to house and distribute collections of protein and genetic interactions from major model organism species. BioGRID currently contains over 198 000 interactions from six different species, as derived from both high-throughput studies and conventional focused studies. Through comprehensive curation efforts, BioGRID now includes a virtually complete set of interactions reported to date in the primary literature for both the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. A number of new features have been added to the BioGRID including an improved user interface to display interactions based on different attributes, a mirror site and a dedicated interaction management system to coordinate curation across different locations. The BioGRID provides interaction data with monthly updates to Saccharomyces Genome Database, Flybase and Entrez Gene. Source code for the BioGRID and the linked Osprey network visualization system is now freely available without restriction.

Indexed as

Databases, GeneticGene Regulatory NetworksProtein Interaction MappingAnimalsCaenorhabditis elegansDatabase Management SystemsDrosophila melanogasterHumansInternetMiceSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsUser-Computer InterfaceSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe Proteins

Identifiers

PMID18000002
PMCPMC2238873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.