ArticleNucleic acids research2008
DIMA 2.0--predicted and known domain interactions.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Function prediction and analysis of mycobacterium tuberculosis hypothetical proteins.International journal of molecular sciences · 2012Article
- DIMA 3.0: Domain Interaction Map.Nucleic acids research · 2011Article
- Inferring protein function by domain context similarities in protein-protein interaction networks.BMC bioinformatics · 2009Article
- DASMIweb: online integration, analysis and assessment of distributed protein interaction data.Nucleic acids research · 2009Article
- DASMI: exchanging, annotating and assessing molecular interaction data.Bioinformatics (Oxford, England) · 2009Article
- Protein function annotation by homology-based inference.Genome biology · 2009Review
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Authors and funding
6 authors.
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Abstract
DIMA-the domain interaction map has evolved from a simple web server for domain phylogenetic profiling into an integrative prediction resource combining both experimental data on domain-domain interactions and predictions from two different algorithms. With this update, DIMA obtains greatly improved coverage at the level of genomes and domains as well as with respect to available prediction approaches. The domain phylogenetic profiling method now uses SIMAP as its backend for exhaustive domain hit coverage: 7038 Pfam domains were profiled over 460 completely sequenced genomes. Domain pair exclusion predictions were produced from 83 969 distinct protein-protein interactions obtained from IntAct resulting in 21 513 domain pairs with significant domain pair exclusion algorithm scores. Additional predictions applying the same algorithm to predicted protein interactions from STRING yielded 2378 high-confidence pairs. Experimental data comes from iPfam (3074) and 3did (3034 pairs), two databases identifying domain contacts in solved protein structures. Taken together, these two resources yielded 3653 distinct interacting domain pairs. DIMA is available at http://mips.gsf.de/genre/proj/dima.
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Registered trials
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