ReviewCurrent neurology and neuroscience reports2007
Progressive multifocal leukoencephalopathy.
Review in Current neurology and neuroscience reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 77 citations in OpenAlex.
- Human glial chimeric mice reveal astrocytic dependence of JC virus infection.The Journal of clinical investigation · 2014Trial
- Article
- Progressive multifocal leukoencephalopathy in a patient with systemic sclerosis treated with methotrexate: A case report and literature review.Journal of scleroderma and related disorders · 2020Article
- JC polyomavirus replication and associated disease in pediatric renal transplantation: an international CERTAIN Registry study.Pediatric nephrology (Berlin, Germany) · 2018Article
- Article
- Discovery and characterization of novel trans-spliced products of human polyoma JC virus late transcripts from PML patients.Journal of cellular physiology · 2018Article
- The national incidence of PML in Sweden, 1988-2013.Neurology · 2018Article
- JC polyomavirus reactivation is common following allogeneic stem cell transplantation and its preemptive detection may prevent lethal complications.Bone marrow transplantation · 2015Article
- Persistence and pathogenesis of the neurotropic polyomavirus JC.Annals of neurology · 2015Review
- Rad51 activates polyomavirus JC early transcription.PloS one · 2014Article
- Cooperative roles of NF-κB and NFAT4 in polyomavirus JC regulation at the KB control element.Virology · 2012Article
- JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons.Journal of cellular physiology · 2012Article
- Pathogenesis of progressive multifocal leukoencephalopathy--revisited.The Journal of infectious diseases · 2011Review
- Progressive multifocal leukoencephalopathy and other forms of JC virus disease.Nature reviews. Neurology · 2010Review
- Toxic leukoencephalopathy after intravenous heroin injection: a case with clinical and radiological reversibility.Journal of neurology · 2010Article
- Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease.Acta neuropathologica · 2010Review
- Stronger association of drug-induced progressive multifocal leukoencephalopathy (PML) with biological immunomodulating agents.European journal of clinical pharmacology · 2010Article
- Large T antigen promotes JC virus replication in G2-arrested cells by inducing ATM- and ATR-mediated G2 checkpoint signaling.The Journal of biological chemistry · 2010Article
- Modulation of JC virus transcription by C/EBPbeta.Virus research · 2009Article
- Emerging viral infections of the central nervous system: part 2.Archives of neurology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Progressive multifocal leukoencephalopathy (PML) was a rare disease until the advent of the HIV/AIDS pandemic. Recent interest in the disorder has been spurred by its appearance in patients treated with the monoclonal antibodies natalizumab and rituximab. Unless the accompanying underlying immune deficit can be reversed, PML typically progresses to death fairly rapidly. Treatment directed against the JC virus has been unhelpful, but an increased understanding of disease pathogenesis may result in effective therapeutic strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.