Evidence map›Paper›PMID 17999762›Full record

ArticleTheoretical biology & medical modelling2007

The Proteomic Code: a molecular recognition code for proteins.

Jan C Biro

Abstract readHistorical Article
In one paragraph

Article in Theoretical biology & medical modelling, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The concept of RNA-assisted protein folding: the role of tRNA.Theoretical biology & medical modelling · 2012
    Article
  9. Article
  10. Article
  11. Article
  12. Discovery of proteomic code with mRNA assisted protein folding.International journal of molecular sciences · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jan C BiroHomulus Foundation, 88 Howard, #1205, San Francisco, CA 94105, USA. jan.biro@comcast.net

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Proteomic Code is a set of rules by which information in genetic material is transferred into the physico-chemical properties of amino acids. It determines how individual amino acids interact with each other during folding and in specific protein-protein interactions. The Proteomic Code is part of the redundant Genetic Code. REVIEW: The 25-year-old history of this concept is reviewed from the first independent suggestions by Biro and Mekler, through the works of Blalock, Root-Bernstein, Siemion, Miller and others, followed by the discovery of a Common Periodic Table of Codons and Nucleic Acids in 2003 and culminating in the recent conceptualization of partial complementary coding of interacting amino acids as well as the theory of the nucleic acid-assisted protein folding. METHODS AND

conclusionsA novel cloning method for the design and production of specific, high-affinity-reacting proteins (SHARP) is presented. This method is based on the concept of proteomic codes and is suitable for large-scale, industrial production of specifically interacting peptides.

Indexed as

Protein FoldingAmino AcidsAmino Acid SequenceAnimalsBase SequenceCodonGenetic CodeHistory, 20th CenturyHistory, 21st CenturyHumansModels, ChemicalMolecular Sequence DataNucleic Acid ConformationProtein BindingProtein ConformationProteinsAmino AcidsCodonProteinsRNARNA, Messenger

Identifiers

PMID17999762
PMCPMC2206014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.