Trial reportJournal of behavioral medicine2008
The efficacy of vitamins for reducing or preventing depression symptoms in healthy individuals: natural remedy or placebo?
Trial report in Journal of behavioral medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases.The Cochrane database of systematic reviews · 2012Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over-the-counter vitamins have become increasingly popular as a natural remedy for reducing or preventing depression symptoms and enhancing the emotional well-being of healthy individuals in the general population. This placebo-controlled, single-blind trial evaluated the effect of vitamins on depression symptoms experienced by a nonclinical sample of participants. One hundred and fourteen healthy young adults were randomly assigned to multivitamin, B-complex vitamin, placebo vitamin, or no-treatment control conditions. At the end of a 6-week regimen, participants administered vitamins reported significant reductions in depression symptoms as measured by the Beck Depression Inventory compared to those who received no treatment. There was no difference between the multivitamin, the B-vitamin, and the placebo. The effect of each of the vitamin regimens on depression symptoms was partially mediated by response expectancies. The results do not support the efficacy of vitamins as a natural remedy for reducing or preventing depression symptoms among healthy people in the general population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.