Evidence map›Paper›PMID 17999098›Full record

ReviewInvertebrate neuroscience : IN2007

Ion-channels on parasite muscle: pharmacology and physiology.

Alan P Robertson, Richard J Martin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Invertebrate neuroscience : IN, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Suppression ofInternational journal of molecular sciences · 2018
    Article
  9. Octopamine signaling in the metazoan pathogenDisease models & mechanisms · 2018
    Article
  10. Article
  11. Review
  12. Functional genomics inProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  13. Article
  14. Review
  15. Ion channels and drug transporters as targets for anthelmintics.Current clinical microbiology reports · 2014
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Calcium channels of schistosomes: unresolved questions and unexpected answers.Wiley interdisciplinary reviews. Membrane transport and signaling · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alan P RobertsonDepartment of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA. alanr@iastate.edu
Richard J Martin

Funding

NIAID NIH HHS R01 AI04719406A1
6 · The paper itself

Abstract

Ion-channels are essential components of excitable cells. This fact has been exploited in the development of anthelmintic agents; the majority of which act on nematode ion channels. The purpose of this review is to describe the site of action of some frequently used anthelmintic compounds: nAChRs and levamisole/pyrantel; Glu-Cls and avermectins/mylbemycins; GABA receptors and piperazine. Also described is some of the physiological and pharmacological data on other nematode muscle ion-channels which may prove attractive targets for future anthelmintic development: Ca2+ activated Cl(-) channels; peptide gated chloride Cl(-) channels; Ca2+ channels and potassium channels. Emphasis is placed on the pharmacological and physiological data from parasite tissue. Information on the genes involved in ion-channel formation and modulation are reviewed in detail elsewhere in this issue.

Indexed as

AnimalsAnthelminticsHelminthsIon ChannelsMusclesAnthelminticsIon Channels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.