ArticleOphthalmology2008
Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino Eye Study.
Article in Ophthalmology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 158 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Detection of Glaucoma Progression Study With Macular OCT Imaging
The eyeGuide: Improving Glaucoma Self-management With a Personalized Behavior Change Program
Malay Glaucoma Eye Study II: Elucidating Navigation, Mobility and Reading Ability to Improve Quality of Life and Progression of Primary Glaucoma
Developing and Testing a Low Cost Opportunistic Glaucoma Screening Model During Diabetic Retinopathy Screening by Non-physician Graders in Vietnam
Evaluation of The Effectiveness Of Reading Rehabilitation Module On Reading Performance And Quality of Life In Patients With Glaucoma
Who cites it
158 citing papers in PubMed, 2 syntheses or guidelines pooled it, 340 citations in OpenAlex.
- Visual field outcomes after cataract surgery with or without microinvasive glaucoma surgery in open-angle glaucoma: a systematic review and meta-analysis of RCTs reporting visual field results.International ophthalmology · 2025Pooled it
- Association between vision impairment and mortality: a systematic review and meta-analysis.The Lancet. Global health · 2021Pooled it
- Primary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS).BMJ (Clinical research ed.) · 2021Trial
- Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol.The British journal of ophthalmology · 2018Trial
- Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study.Scientific reports · 2018Trial
- Development of an 18-Item Measure of Symptom Burden in Patients With Glaucoma From the Collaborative Initial Glaucoma Treatment Study's Symptom and Health Problem Checklist.JAMA ophthalmology · 2017Trial
- Binocular Measures of Visual Acuity and Visual Field versus Binocular Approximations.Ophthalmology · 2017Trial
- Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up.Acta ophthalmologica · 2015Trial
- Trial
- Estimating minimally important differences for two vision-specific quality of life measures.Investigative ophthalmology & visual science · 2014Trial
- The impact of structural and functional parameters in glaucoma patients on patient-reported visual functioning.PloS one · 2013Trial
- Evaluating clinical change and visual function concerns in drivers and nondrivers with glaucoma.Investigative ophthalmology & visual science · 2009Trial
- Article
- Fast Progressors in Primary Open-Angle Glaucoma: A 5-Year Visual Field Index-Based Classification in a Real-World Cohort.Ophthalmology and therapy · 2026Article
- Modalities of vision restoration in optic neuropathies and retinal disease.Progress in retinal and eye research · 2026Review
- Archetypes of Binocular Visual Field Loss and Their Impact on Vision-Related Quality of Life in Glaucoma Patients.Investigative ophthalmology & visual science · 2026Article
- Ophthalmologists' Perceptions of the Impact of Patient Mental Status on Clinical Decision-Making: A Cross-Sectional Survey.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Dual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction.Translational vision science & technology · 2025Article
- Improvement in vision-related quality-of-life using the NEI-VFQ-9 over 1-year in the Manhattan Vision Screening and Follow-up Study (NYC-SIGHT).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Understanding Glaucoma: Why it Remains a Leading Cause of Blindness Worldwide.Klinische Monatsblatter fur Augenheilkunde · 2025Review
98 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo examine the association between health-related quality of life (HRQOL) and visual field (VF) loss in participants with open-angle glaucoma (OAG) in the Los Angeles Latino Eye Study (LALES).
designPopulation-based cross-sectional study.
participantsTwo hundred thirteen participants with OAG and 2821 participants without glaucoma or VF loss.
methodsParticipants in the LALES-a population-based prevalence study of eye disease in Latinos 40 years and older, residing in Los Angeles, California-underwent a detailed eye examination including an assessment of their VF using the Humphrey Automated Field Analyzer (Swedish interactive thresholding algorithm Standard 24-2). Open-angle glaucoma was determined by clinical examination. Mean deviation scores were used to assess severity of VF loss. Health-related QOL was assessed by the Medical Outcomes Study 12-item Short-Form Health Survey (SF-12) and 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Linear regression and analysis of covariance were used to assess the relationship between HRQOL scores and VF loss after adjusting for sociodemographic variables and visual acuity.
main outcome measuresThe 25-item NEI-VFQ and SF-12 scores.
resultsA trend of worse NEI-VFQ-25 scores for most subscales was observed with worse VF loss (using both monocular and calculated binocular data). Open-angle glaucoma participants with VF loss had lower scores than participants with no VF loss. This association was also present in participants who were previously undiagnosed and untreated for OAG (N = 160). Participants with any central VF loss had lower NEI-VFQ-25 scores than those with unilateral or bilateral peripheral VF loss. There was no significant impact of severity or location of VF loss on SF-12 scores.
conclusionGreater severity of VF loss in persons with OAG impacts vision-related QOL. This impact was present in persons who were previously unaware that they had glaucoma. Prevention of VF loss in persons with glaucoma is likely to reduce loss of vision-related QOL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.