Evidence map›Paper›PMID 17993737›Full record

ReviewNeonatology2008

Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage.

Olaf Dammann, Wolfgang Bueter, Alan Leviton, Pierre Gressens, Christiane E L Dammann

Open access · greenAbstract readReview
In one paragraph

Review in Neonatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Extreme prematurity: Risk and resiliency.Current problems in pediatric and adolescent health care · 2022
    Review
  3. Review
  4. Article
  5. Impact of theOpen access Macedonian journal of medical sciences · 2019
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cytokines and perinatal brain damage.Clinics in perinatology · 2008
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Olaf DammannDivision of Newborn Medicine, Department of Pediatrics, Tufts-New England Medical Center, Boston, Mass., USA. odammann@tufts-nemc.org
Wolfgang Bueter
Alan Leviton
Pierre Gressens
Christiane E L Dammann
Tufts Medical Center · USHarvard University · USInserm · FRMedizinische Hochschule Hannover · DE

Funding

Neonatal Biomarkers in Extremely Preterm Babies Predict Childhood Brain DisordersU01NS040069 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI KUBAN, KARL · 2001 to 2014
$34.0M
SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI FAGIOLINI, MICHELA · 1985 to 2015
$26.2M
NEUREGULINS AND THEIR RECEPTORS IN LUNG DEVELOPMENTK08HL004436 · NHLBI · TUFTS MEDICAL CENTER · PI DAMMANN, CHRISTIANE E · 2001 to 2005
$649k
NHLBI NIH HHS K08 HL004436NICHD NIH HHS P30 HD018655NINDS NIH HHS U01 NS040069
6 · The paper itself

Abstract

Brain white matter damage, an important antecedent of long-term disabilities among preterm infants, has both endogenous and exogenous components. One of the endogenous components is the paucity of developmentally regulated protectors. Here we expand on this component, discussing the potential roles of one putative protector, neuregulin (NRG)-1, in brain development and damage. We outline how NRG-1 might be involved in perinatal brain damage pathomechanisms and suggest that NRG-1 might be one target for intervention.

Indexed as

AnimalsBrainBrain DiseasesHumansInfant, NewbornInfant, PrematureNeuregulin-1RatsReceptor Protein-Tyrosine KinasesNeuregulin-1Receptor Protein-Tyrosine Kinases

Identifiers

PMID17993737
PMCPMC2910616
OpenAlexW1988054680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.