ArticleApplied and environmental microbiology2008
Transcriptome analysis of Lactococcus lactis in coculture with Saccharomyces cerevisiae.
Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
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- COmmunity and Single Microbe Optimisation System (COSMOS).NPJ systems biology and applications · 2025Article
- Discovery and delivery strategies for engineered live biotherapeutic products.Trends in biotechnology · 2022Review
- Synergistic Regulation of Transcription and Translation in Escherichia coli Revealed by Codirectional Increases in mRNA Concentration and Translation Efficiency.Microbiology spectrum · 2022Article
- The forgotten role of food cultures.FEMS microbiology letters · 2021Review
- Multiplexing polysome profiling experiments to study translation in Escherichia coli.PloS one · 2019Article
- Food Spoilage-Associated Leuconostoc, Lactococcus, and Lactobacillus Species Display Different Survival Strategies in Response to Competition.Applied and environmental microbiology · 2018Article
- The stability of an mRNA is influenced by its concentration: a potential physical mechanism to regulate gene expression.Nucleic acids research · 2017Article
- Transcriptional Responses of the Bacterium Burkholderia terrae BS001 to the Fungal Host Lyophyllum sp. Strain Karsten under Soil-Mimicking Conditions.Microbial ecology · 2017Article
- Transcriptomic Responses of the Interactions between Clostridium cellulovorans 743B and Rhodopseudomonas palustris CGA009 in a Cellulose-Grown Coculture for Enhanced Hydrogen Production.Applied and environmental microbiology · 2016Article
- Improving flavor metabolism of Saccharomyces cerevisiae by mixed culture with Bacillus licheniformis for Chinese Maotai-flavor liquor making.Journal of industrial microbiology & biotechnology · 2015Article
- Genomic expression program of Saccharomyces cerevisiae along a mixed-culture wine fermentation with Hanseniaspora guilliermondii.Microbial cell factories · 2015Article
- Article
- Transcriptome-based characterization of interactions between Saccharomyces cerevisiae and Lactobacillus delbrueckii subsp. bulgaricus in lactose-grown chemostat cocultures.Applied and environmental microbiology · 2013Article
- Bacterial-fungal interactions: hyphens between agricultural, clinical, environmental, and food microbiologists.Microbiology and molecular biology reviews : MMBR · 2011Review
- Dual transcriptional profiling of a bacterial/fungal confrontation: Collimonas fungivorans versus Aspergillus niger.The ISME journal · 2011Article
- Assessment of the diversity of dairy Lactococcus lactis subsp. lactis isolates by an integrated approach combining phenotypic, genomic, and transcriptomic analyses.Applied and environmental microbiology · 2011Article
- Proteomics and transcriptomics characterization of bile stress response in probiotic Lactobacillus rhamnosus GG.Molecular & cellular proteomics : MCP · 2011Article
- Stable coexistence of two Caldicellulosiruptor species in a de novo constructed hydrogen-producing co-culture.Microbial cell factories · 2010Article
- Investigation of associations of Yarrowia lipolytica, Staphylococcus xylosus, and Lactococcus lactis in culture as a first step in microbial interaction analysis.Applied and environmental microbiology · 2009Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study of microbial interactions in mixed cultures remains an important conceptual and methodological challenge for which transcriptome analysis could prove to be the essential method for improving our understanding. However, the use of whole-genome DNA chips is often restricted to the pure culture of the species for which the chips were designed. In this study, massive cross-hybridization was observed between the foreign cDNA and the specific Lactococcus lactis DNA chip. A very simple method is proposed to considerably decrease this nonspecific hybridization, consisting of adding the microbial partner's DNA. A correlation was established between the resulting cross-hybridization and the phylogenetic distance between the microbial partners. The response of L. lactis to the presence of Saccharomyces cerevisiae was analyzed during the exponential growth phase in fermentors under defined growth conditions. Although no differences between growth kinetics were observed for the pure and the mixed cultures of L. lactis, the mRNA levels of 158 genes were significantly modified. More particularly, a strong reorientation of pyrimidine metabolism was observed when L. lactis was grown in mixed cultures. These changes in transcript abundance were demonstrated to be regulated by the ethanol produced by the yeast and were confirmed by an independent method (quantitative reverse transcription-PCR).
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