ReviewClinical reviews in allergy & immunology2007
Clinical, immunologic, and molecular factors predicting lymphoma development in Sjogren's syndrome patients.
Review in Clinical reviews in allergy & immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Identification of lymphoma predictors in patients with primary Sjögren's syndrome: a systematic literature review and meta-analysis.Rheumatology international · 2015Pooled it
- Prognostic benefit of immunosuppressive agents in primary Sjögren's syndrome patients with hypergammaglobulinemia.Frontiers in immunology · 2026Article
- Primary Breast Extranodal Marginal Zone Lymphoma in Primary Sjögren Syndrome: Case Presentation and Relevant Literature.Journal of clinical medicine · 2020Article
- Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.Rheumatology international · 2020Observational
- Extraglandular ocular involvement and morbidity and mortality in primary Sjögren's Syndrome.PloS one · 2020Article
- Sjögren's Syndrome: More Than Just Dry Eye.Cornea · 2019Review
- Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis.Clinical immunology (Orlando, Fla.) · 2018Article
- Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren's syndrome mice.Scientific reports · 2017Article
- What can Sjögren's syndrome-like disease in mice contribute to human Sjögren's syndrome?Clinical immunology (Orlando, Fla.) · 2017Review
- Association of Dry Eye Tests With Extraocular Signs Among 3514 Participants in the Sjögren's Syndrome International Registry.American journal of ophthalmology · 2016Article
- The Proteomics of Saliva in Sjögren's Syndrome.Rheumatic diseases clinics of North America · 2016Review
- Tubulointerstitial nephritis in primary Sjögren syndrome: clinical manifestations and response to treatment.BMC musculoskeletal disorders · 2016Article
- Sjögren's Syndrome Complicated by Myeloid/Natural Killer Cell Precursor Acute Leukemia: Case Report and Review of the Literature.Case reports in hematology · 2016Article
- Adjuvants and lymphoma risk as part of the ASIA spectrum.Immunologic research · 2015Review
- Absence of somatic MYD88 L265P mutations in patients with primary Sjogren's syndrome.Genes and immunity · 2014Article
- Cancer risk in systemic lupus: an updated international multi-centre cohort study.Journal of autoimmunity · 2013Article
- Possible Mechanisms of Lymphoma Development in Sjögren's Syndrome.Current immunology reviews · 2013Article
- Relation of sensory peripheral neuropathy in Sjögren syndrome to anti-Ro/SSA.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2012Article
- Advances in the Aetiophatogenesis of Sjögren's Syndrome: a Literature Review.Journal of oral & maxillofacial research · 2012Review
- Malignant lymphomas and autoimmunity-a single center experience from Hungary.Clinical rheumatology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among autoimmune diseases, Sjogren's syndrome (SS) displays the highest incidence of non-Hodgkin lymphoma (NHL) development with the salivary extranodal marginal zone B cell lymphomas being the most common type. The majority of SS-associated NHLs are characterized by localized stage, indolent clinical course, and recurrence in other extranodal sites. Although the transition from a chronic inflammatory condition to malignant lymphoma is a multistep process yet poorly understood, there is increasing evidence that chronic antigenic stimulation by an exoantigen or autoantigens plays an essential role in the development of SS associated lymphoproliferation. Additional molecular oncogenic events such as microsatellite instability, loss of the B cell cycle control, and the forced overproduction of specific B cell biologic stimulators seem to contribute to the emergence and progression of the malignant overgrowth. Among the clinical and serological parameters that have been associated with lymphoma development in SS patients, the presence of palpable purpura, low C4, and mixed monoclonal cryoglobulinemia constitute the main predictive markers, and patients displaying these risk factors should be monitored closely.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.