Evidence map›Paper›PMID 17992253›Full record

ArticleCancer informatics2007

Computational methods for the analysis of array comparative genomic hybridization.

Raj Chari, William W Lockwood, Wan L Lam

Abstract read
In one paragraph

Article in Cancer informatics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. aCGH.Spline--an R package for aCGH dye bias normalization.Bioinformatics (Oxford, England) · 2011
    Article
  5. Review
  6. A double-layered mixture model for the joint analysis of DNA copy number and gene expression data.Journal of computational biology : a journal of computational molecular cell biology · 2010
    Article
  7. Article
  8. Multiple aberrations of chromosome 3p detected in oral premalignant lesions.Cancer prevention research (Philadelphia, Pa.) · 2008
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raj ChariCancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver BC, Canada V5Z 1L3. rchari@bccrc.ca
William W Lockwood
Wan L Lam

Funding

Whole genome array CGH of progressing oral dysplasiaR01DE015965 · NIDCR · BRITISH COLUMBIA CANCER AGENCY · PI LAM, WAN L · 2004 to 2007
$1.1M
NIDCR NIH HHS R01 DE015965
6 · The paper itself

Abstract

Array comparative genomic hybridization (array CGH) is a technique for assaying the copy number status of cancer genomes. The widespread use of this technology has lead to a rapid accumulation of high throughput data, which in turn has prompted the development of computational strategies for the analysis of array CGH data. Here we explain the principles behind array image processing, data visualization and genomic profile analysis, review currently available software packages, and raise considerations for future software development.

Indexed as

alteration detectionarray CGHbioinformaticscancer genomemicroarraysoftware

Identifiers

PMID17992253
PMCPMC2067254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.