Evidence map›Paper›PMID 17991935›Full record

Trial reportBMJ (Clinical research ed.)2007

Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial.

Nudrat Noor Qureshi, Juanita Hatcher, Nish Chaturvedi, Tazeen H Jafar, Hypertension Research Group

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00330408 (Impact of Training of GPs on Adherence of Hypertensive Individuals to Antihypertensive Medication), which is not on this map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00330408 naunknown statusnot on this map

Impact of Training of GPs on Adherence of Hypertensive Individuals to Antihypertensive Medication

TypeinterventionalSponsorAga Khan UniversityRan2005 to 2006Enrolled178ConditionsHypertensionArmsGP training
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nudrat Noor QureshiClinical Epidemiology Unit, Department of Community Health Sciences, Aga Khan University, P O Box 3500, Stadium Road, Karachi, 74800, Pakistan.
Juanita Hatcher
Nish Chaturvedi
Tazeen H Jafar
Hypertension Research Group

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveTo determine the impact of a simple educational package for general practitioners on adherence to antihypertensive drugs.

designCluster randomised controlled trial.

settingSix randomly selected communities in Karachi, Pakistan.

participants200 patients with hypertension taking antihypertensive drugs; 78 general practitioners.

interventionCare by general practitioners specially trained in management of hypertension compared with usual care.

main outcome measureCorrect dosing, defined as percentage of prescribed doses taken, measured with electronic medication event monitoring system (MEMS) bottle.

results200 patients were enrolled, and 178 (89%) successfully completed six weeks of follow-up. Adherence was significantly greater in the special care group than in the usual care group (unadjusted mean percentage days with correct dose 48.1%, 95% confidence interval 35.8% to 60.4%, versus 32.4%, 22.6% to 42.3%; P=0.048). Adherence was also higher among patients who had higher levels of education (P<0.001), were encouraged by family members (P<0.001), believed in the effect of drugs (P<0.001), and had the purpose of the drugs explained to them (P<0.001).

conclusionsSpecial training of general practitioners in management of hypertension, emphasising good communication between doctors and patients, is more effective than usual care provided in the communities in Karachi. Such simple interventions should be adopted by other developing countries that are now facing an increasing burden of hypertension.

trial registrationClinical trials NCT00330408 [ClinicalTrials.gov].

Indexed as

Education, Medical, GraduatePatient ComplianceAdultAgedAntihypertensive AgentsCluster AnalysisFamily PracticeHumansHypertensionMiddle AgedPakistanAntihypertensive Agents

Identifiers

PMID17991935
PMCPMC2078673

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.