ReviewCurrent gastroenterology reports2007
Drug-induced diarrhea.
Review in Current gastroenterology reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 69 citations in OpenAlex.
- Role of Bile Acid Receptors in Non-Infectious Diarrhea: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Adjunctive use ofTranslational gastroenterology and hepatology · 2026Article
- Restore intestinal steady-state: new advances in the clinical management of chemotherapy-associated diarrhea and constipation.Journal of molecular histology · 2025Review
- COVID-19 and diarrhea: putative mechanisms and management.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023Review
- Nonsteroidal anti-inflammatory drug exposure and the risk of microscopic colitis.BMC gastroenterology · 2022Article
- Effects of Ethanol Extracts fromMarine drugs · 2021Article
- Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea.Toxicological sciences : an official journal of the Society of Toxicology · 2019Article
- Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers.Frontiers in pharmacology · 2017Article
- The pharmacologic treatment of short bowel syndrome: new tricks and novel agents.Current gastroenterology reports · 2014Review
- Nosocomial diarrhea: evaluation and treatment of causes other than Clostridium difficile.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012Review
- Evaluating the patient with diarrhea: a case-based approach.Mayo Clinic proceedings · 2012Article
- [Nosocomial diarrhea].Der Internist · 2011Article
- Diagnosis by inclusion.NDT plus · 2008Article
- Diarrhea in Placebo Arms of Cancer Studies.Cancer diagnosis & prognosisReview
- Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter.Molecular pharmaceuticsArticle
- Article
- Self-limiting diarrhea in an infant exposed to sertraline in breast milk.Journal of family medicine and primary careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many drugs have been known to cause diarrhea, although their mechanism of action has not been well described. The gastrointestinal tract may become dysregulated when exposed to a drug that could disrupt mechanisms controlling mucosal permeability, transport, motility, and gut metabolism. This review examines the mechanism by which drugs induce diarrhea within the broad classification of watery, inflammatory, and fatty characteristics of the stool. Treatment may vary depending on this classification and usually includes withdrawal of the offending drug. However, in some cases, diarrhea may resolve with continued use or through nonspecific agents, such as Lomotil (Pfizer, New York, NY) or loperamide.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.