Evidence map›Paper›PMID 17990112›Full record

ArticleDigestive diseases and sciences2008

Autonomic function at rest and in response to emotional and rectal stimuli in women with irritable bowel syndrome.

Signe Spetalen, Leiv Sandvik, Svein Blomhoff, Morten B Jacobsen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02874495 (Anticipation Effect on Painful Phenomenons Linked to Rectal Distension for Patients With a Crohn's Disease in Remission), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02874495 unknown statusnot on this mapstarted 2012, after this paper: background citation

Anticipation Effect on Painful Phenomenons Linked to Rectal Distension for Patients With a Crohn's Disease in Remission: Functional MRI Study

TypeobservationalSponsorUniversity Hospital, GrenobleRan2012 to 2017Enrolled44ConditionsCrohn's DiseaseArmsPsychological tests, Magnetic Resonance Imaging, Heart Rate Variability
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
  6. Autonomic predictors of recovery following surgery: a comparative study.Autonomic neuroscience : basic & clinical · 2010
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Signe SpetalenDepartment of Medicine, Rikshospitalet University Hospital, Oslo, Norway. signe.spetalen@ulleval.no
Leiv Sandvik
Svein Blomhoff
Morten B Jacobsen
Oslo University Hospital · NOØstfold Hospital Trust · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to study autonomic function in patients with Irritable bowel syndrome (IBS) without constipation and psychiatric comorbidity. Respiratory sinus arrhythmia (RSA) (representing cardiac vagal activity), skin conductance (representing sympathetic activity) and heart rate were measured at baseline and as a response to emotional stress and rectal discomfort in 33 women with IBS and 21 healthy women. Baseline heart rate was higher in the patients than in the healthy volunteers. Both groups had decreased RSA and increased heart rate and skin conductance level when exposed to emotional stress, but the autonomic responses did not differ significantly between the groups. At discomfort threshold the patients had increased heart rate response and skin conductance amplitude when compared to the healthy volunteers. Correlations between autonomic responses and the depression subscale of the Hospital Anxiety and Depression (HAD) score differed markedly between the diarrhea-predominant IBS patients and the IBS patients with alternating stool habits.

Indexed as

AdultArrhythmia, SinusAutonomic Nervous SystemElectric ConductivityFemaleHeart RateHumansIrritable Bowel SyndromeManometryMiddle AgedRectumRestSkinStress, Psychological

Identifiers

PMID17990112
OpenAlexW2109592142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.