ReviewJournal of bioenergetics and biomembranes2007
ABCG transporters: structure, substrate specificities and physiological roles : a brief overview.
Review in Journal of bioenergetics and biomembranes, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 86 citations in OpenAlex.
- ABCG2 transporter: Structural and functional associations with gout (Review).International journal of molecular medicine · 2026Review
- Structural insights into AtABCG25, an angiosperm-specific abscisic acid exporter.Plant communications · 2024Article
- Insights into the involvement of long non-coding RNAs in doxorubicin resistance of cancer.Frontiers in pharmacology · 2023Review
- The putative ABCG transporterPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Article
- The Effect of Necrotic Enteritis Challenge on Production Performance, Cecal Microbiome, and Cecal Tonsil Transcriptome in Broilers.Pathogens (Basel, Switzerland) · 2022Article
- ABC transporters control ATP release through cholesterol-dependent volume-regulated anion channel activity.The Journal of biological chemistry · 2020Article
- Polymorphisms of xenobiotic-metabolizing and transporter genes, and the risk of gastric and colorectal cancer in an admixed population from the Brazilian Amazon.American journal of translational research · 2020Article
- Effects of diethylcarbamazine and ivermectin treatment onParasitology open · 2019Article
- Renal Drug Transporters and Drug Interactions.Clinical pharmacokinetics · 2017Review
- ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation.Journal of lipid research · 2015Article
- A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole.Memorias do Instituto Oswaldo Cruz · 2015Article
- Investigation of the functional single-nucleotide polymorphisms in theBiomedical reports · 2015Article
- The role of Arabidopsis ABCG9 and ABCG31 ATP binding cassette transporters in pollen fitness and the deposition of steryl glycosides on the pollen coat.The Plant cell · 2014Article
- The Transformer database: biotransformation of xenobiotics.Nucleic acids research · 2014Article
- Effects of a fixed-intensity of endurance training and pistacia atlantica supplementation on ATP-binding cassette G4 expression.Chinese medicine · 2013Article
- Role of Homeodomain leucine zipper (HD-Zip) IV transcription factors in plant development and plant protection from deleterious environmental factors.International journal of molecular sciences · 2013Review
- Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications.The pharmacogenomics journal · 2013Review
- Maternal ABCA1 genotype is associated with severity of Smith-Lemli-Opitz syndrome and with viability of patients homozygous for null mutations.European journal of human genetics : EJHG · 2013Article
- Emodin as an effective agent in targeting cancer stem-like side population cells of gallbladder carcinoma.Stem cells and development · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The ATP-binding cassette (ABC) transporter superfamily is one of the largest protein families with representatives in all kingdoms of life. Members of this superfamily are involved in a wide variety of transport processes with substrates ranging from small ions to relatively large polypeptides and polysaccharides. The G subfamily of ABC transporters consists of half-transporters, which oligomerise to form the functional transporter. While ABCG1, ABCG4 and ABCG5/8 are involved in the ATP-dependent translocation of steroids and, possibly, other lipids, ABCG2 (also termed the breast cancer resistance protein) has been identified as a multidrug transporter that confers resistance on tumor cells. Evidence will be summarized suggesting that ABCG2 can also mediate the binding/transport of non-drug substrates, including free and conjugated steroids. The characterization of the substrate specificities of ABCG proteins at a molecular level might provide further clues about their potential physiological role(s), and create new opportunities for the modulation of their activities in relation to human disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.