Evidence map›Paper›PMID 17990082›Full record

ArticleJournal of materials science. Materials in medicine2008

Carboxymethyl cellulose (CMC) based semi-IPNs as carriers for controlled release of ciprofloxacine: an in-vitro dynamic study.

A K Bajpai, Abhilasha Mishra

Abstract read
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In one paragraph

Article in Journal of materials science. Materials in medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antimicrobial ZnGels (Basel, Switzerland) · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

A K BajpaiBose Memorial Research Laboratory, Department of Chemistry, Government Autonomous Science College, Jabalpur, MP 482 001, India. akbmrl@yahoo.co.in
Abhilasha Mishra

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semi-interpenetrating polymer networks (IPNs) of carboxymethyl cellulose (CMC) and polyacrylic acid were prepared and its potential for controlled release of ciprofloxacine (Cfx) was assessed. The IPNs were characterized by IR spectral analysis and Environmental scanning electron microscopy (ESEM). The entrapped drug was examined for its antibacterial activity and chemical stability. The effects of experimental parameters such as varying chemical composition of the IPNs, percent loading of Cfx, pH and temperature of release medium and presence of salt ions in outer solution were examined on the release profile of the drug. On the basis of Fick's power law equations, the diffusion exponents (n) and diffusion constant (D) were evaluated for different IPNs compositions. From the kinetic parameter data, an attempt was made to resolve the mechanism of the release process of Cfx.

Indexed as

Acrylic ResinsCarboxymethylcellulose SodiumCiprofloxacinCross-Linking ReagentsDiffusionDose-Response Relationship, DrugDrug CarriersDrug Delivery SystemsHydrogen-Ion ConcentrationKineticsMaterials TestingMicroscopy, Electron, ScanningNucleic Acid Synthesis InhibitorsPolymersSpectrophotometry, InfraredSpectroscopy, Fourier Transform InfraredAcrylic Resinscarbopol 940Carboxymethylcellulose SodiumCiprofloxacinCross-Linking ReagentsDrug CarriersNucleic Acid Synthesis InhibitorsPolymers

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.