Evidence map›Paper›PMID 17990016›Full record

ArticleJournal of industrial microbiology & biotechnology2008

Actinomycetemcomitin: a new bacteriocin produced by Aggregatibacter (Actinobacillus) actinomycetemcomitans.

Francisca Lúcia Lima, Maria Auxiliadora Roque de Carvalho, Ana Carolina Morais Apolônio, Marcelo Porto Bemquerer, Marcelo Matos Santoro, Jamil Silvano Oliveira, Celuta Sales Alviano, Luiz de Macêdo Farias

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In one paragraph

Article in Journal of industrial microbiology & biotechnology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Francisca Lúcia LimaInstituto de Microbiologia Prof. Paulo de Góes, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Maria Auxiliadora Roque de Carvalho
Ana Carolina Morais Apolônio
Marcelo Porto Bemquerer
Marcelo Matos Santoro
Jamil Silvano Oliveira
Celuta Sales Alviano
Luiz de Macêdo Farias
Universidade Federal de Minas Gerais · BRUniversidade Estadual do Piau · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggregatibacter (Actinobacillus) actinomycetemcomitans P(7-20) strain isolated from a periodontally diseased patient has produced a bacteriocin (named as actinomycetemcomitin) that is active against Peptostreptococcus anaerobius ATCC 27337. Actinomycetemcomitin was produced during exponential and stationary growth phases, and its amount decreased until it disappeared during the decline growth phase. It was purified by ammonium sulphate precipitation (30-60% saturation), and further by FPLC (mono-Q ionic exchange and Phenyl Superose hydrophobic interaction) and HPLC (C-18 reversed-phase). This bacteriocin loses its activity after incubation at a pH below 7.0 or above 8.0, following heating for 30 min at 45 degrees C, and after treatment with proteolytic enzymes such as trypsin, alpha-chymotrypsin, and papain. Actinomycetemcomitin has a molecular mass of 20.3 KDa and it represents a new bacteriocin from A. actinomycetemcomitans.

Indexed as

Aggregatibacter actinomycetemcomitansAmino Acid SequenceAmmonium SulfateAnti-Bacterial AgentsBacteriocinsChromatography, High Pressure LiquidChromatography, LiquidFractional PrecipitationHumansHydrogen-Ion ConcentrationMolecular Sequence DataMolecular WeightPeptide HydrolasesPeptostreptococcusPeriodontitisSequence AlignmentAmmonium SulfateAnti-Bacterial AgentsBacteriocinsPeptide Hydrolases

Identifiers

PMID17990016
OpenAlexW2032195796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.