ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2007
Auditory-dependent vocal recovery in adult male zebra finches is facilitated by lesion of a forebrain pathway that includes the basal ganglia.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- High-throughput assessment of vocal modulation following chemogenetic inhibition in songbirds.iScience · 2026Article
- Foxp2 mutations and abnormal brain and gastrointestinal development: insights from animal models of speech-language and autism spectrum disorders.Frontiers in neuroanatomy · 2026Review
- Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits.bioRxiv : the preprint server for biology · 2024Article
- Unsupervised restoration of a complex learned behavior after large-scale neuronal perturbation.Nature neuroscience · 2024Article
- ΔCannabis and cannabinoid research · 2023Article
- Cannabidiol inhibits neuroinflammatory responses and circuit-associated synaptic loss following damage to a songbird vocal pre-motor cortical-like region.Scientific reports · 2023Article
- Neuroendocrine patterns underlying seasonal song and year-round territoriality in male black redstarts.Frontiers in zoology · 2021Article
- Manipulations of inhibition in cortical circuitry differentially affect spectral and temporal features of Bengalese finch song.Journal of neurophysiology · 2020Article
- Naturalistic stimulation drives opposing heterosynaptic plasticity at two inputs to songbird cortex.Nature neuroscience · 2015Article
- VoICE: A semi-automated pipeline for standardizing vocal analysis across models.Scientific reports · 2015Article
- Imaging auditory representations of song and syllables in populations of sensorimotor neurons essential to vocal communication.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Independent premotor encoding of the sequence and structure of birdsong in avian cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Long-distance retinoid signaling in the zebra finch brain.PloS one · 2014Article
- Differential contributions of basal ganglia and thalamus to song initiation, tempo, and structure.Journal of neurophysiology · 2014Article
- Developmental pattern of diacylglycerol lipase-α (DAGLα) immunoreactivity in brain regions important for song learning and control in the zebra finch (Taeniopygia guttata).Journal of chemical neuroanatomy · 2013Article
- Translating birdsong: songbirds as a model for basic and applied medical research.Annual review of neuroscience · 2013Review
- Anatomical plasticity in the adult zebra finch song system.The Journal of comparative neurology · 2012Article
- Variable sequencing is actively maintained in a well learned motor skill.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Axial organization of a brain region that sequences a learned pattern of behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Adult neurogenesis is associated with the maintenance of a stereotyped, learned motor behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
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4 authors.
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Abstract
The integration of two neural pathways generates learned song in zebra finches. The vocal motor pathway (VMP) is a direct connection between HVC (proper name) and the robust nucleus of the arcopallium (RA), whereas the anterior forebrain pathway (AFP) comprises an indirect circuit from HVC to RA that traverses the basal ganglia. Partial ablation (microlesion) of HVC in adult birds alters the integration of VMP and AFP synaptic input within RA and destabilizes singing. However, the vocal pattern shows surprising resilience because birds subsequently recover their song in approximately 1 week. Here, we show that deafening prevents vocal recovery after HVC microlesions, indicating that birds require auditory feedback to restore/relearn their vocal patterns. We then tested the role of the AFP (basal ganglia circuit) in this feedback-based recovery by ablating the output nucleus of the AFP [lateral magnocellular nucleus of the anterior nidopallium (LMAN)]. We found that LMAN ablation after HVC microlesions induced a sudden recovery of the vocal pattern. Thus, the AFP cannot be the neural locus of an instructive/learning mechanism that uses auditory feedback to guide vocal recovery, at least in this form of adult vocal plasticity. Instead, the AFP appears to be the source of the variable motor patterns responsible for vocal destabilization. In part, auditory feedback may restore song by strengthening the VMP component of synaptic input to RA relative to the AFP component.
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