SynthesisPostgraduate medical journal2007
A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.
Synthesis in Postgraduate medical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic and meta-analysis review on the diagnostic accuracy of antibodies in the serological diagnosis of COVID-19.Systematic reviews · 2021Pooled it
- Clinical Evaluation of a Tandem qPCR-CRISPR Assay for Multidrug-Resistant or Rifampicin-Resistant Tuberculosis: A Prospective Diagnostic Accuracy Study.Microorganisms · 2026Article
- Blinded trial of multiplex serodiagnostic test in India for diverse forms of active tuberculosis.Microbiology spectrum · 2026Article
- Epidemiology of tuberculosis and HIV coinfection among inpatients in chengdu, china, 2018-2022.BMC infectious diseases · 2025Article
- Machine learning of immune-related laboratory indicators enables discrimination between pulmonary and extrapulmonary tuberculosis.Frontiers in medicine · 2025Article
- Diagnostic efficacy of endobronchial ultrasound-guided transbronchoscopic lung biopsy for identifying tuberculous nodules.BMC infectious diseases · 2024Article
- Cardiac Tuberculosis: A Case Series from Ethiopia, Italy, and Uganda and a Literature Review.The American journal of tropical medicine and hygiene · 2024Review
- Leveraging Antibody, B Cell and Fc Receptor Interactions to Understand Heterogeneous Immune Responses in Tuberculosis.Frontiers in immunology · 2022Review
- Article
- Diagnostic Procedures, Diagnoses, and Treatment Outcomes of Patients with Presumptive Tuberculosis Pleural Effusion in Uzbekistan.International journal of environmental research and public health · 2021Article
- Rifampin resistance among individuals with extrapulmonary tuberculosis: 4 years of experience from a reference laboratory.New microbes and new infections · 2021Article
- Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis.BMC immunology · 2018Article
- T7 Phage Display Library a Promising Strategy to Detect Tuberculosis Specific Biomarkers.Mycobacterial diseases : tuberculosis & leprosy · 2016Article
- Article
- Breast Tuberculosis.The Indian journal of surgery · 2015Review
- Antibodies against Mycobacterial proteins as biomarkers for HIV-associated smear-negative tuberculosis.Clinical and vaccine immunology : CVI · 2014Article
- Differential expression of immunogenic proteins on virulent Mycobacterium tuberculosis clinical isolates.BioMed research international · 2014Article
- Immunogenicity of mycobacterial vesicles in humans: identification of a new tuberculosis antibody biomarker.Tuberculosis (Edinburgh, Scotland) · 2013Article
- Antibody responses to mycobacterial antigens in children with tuberculosis: challenges and potential diagnostic value.Clinical and vaccine immunology : CVI · 2012Review
- Comparative evaluation of profiles of antibodies to mycobacterial capsular polysaccharides in tuberculosis patients and controls stratified by HIV status.Clinical and vaccine immunology : CVI · 2012Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conventional diagnostic tests for tuberculosis have several limitations and are often unhelpful in establishing the diagnosis of extrapulmonary tuberculosis. Although commercial serological antibody based tests are available, their usefulness in the diagnosis of extrapulmonary tuberculosis is unknown. A systematic review was conducted to assess the accuracy of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. In a comprehensive search, 21 studies that reported data on sensitivity and specificity for extrapulmonary tuberculosis were identified. These studies evaluated seven different commercial tests, with Anda-TB IgG accounting for 48% of the studies. The results showed that (1) all commercial tests provided highly variable estimates of sensitivity (range 0.00-1.00) and specificity (range 0.59-1.00) for all extrapulmonary sites combined; (2) the Anda-TB IgG kit showed highly variable sensitivity (range 0.26-1.00) and specificity (range 0.59-1.00) for all extrapulmonary sites combined; (3) for all tests combined, sensitivity estimates for both lymph node tuberculosis (range 0.23-1.00) and pleural tuberculosis (range 0.26-0.59) were poor and inconsistent; and (4) there were no data to determine the accuracy of the tests in children or in patients with HIV infection, the two groups for which the test would be most useful. At present, commercial antibody detection tests for extrapulmonary tuberculosis have no role in clinical care or case detection.
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