Evidence map›Paper›PMID 17989206›Full record

ArticleAmerican journal of physiology. Cell physiology2008

Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach".

George G Holz, Emma Heart, Colin A Leech

Abstract readEditorialComment
In one paragraph

Article in American journal of physiology. Cell physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  8. Article
  9. Elements of the cellular metabolic structure.Frontiers in molecular biosciences · 2015
    Article
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  11. Article
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

George G Holz
Emma Heart
Colin A Leech
New York University · USMarine Biological Laboratory · US

Funding

VOLTAMMETRIC DETECTION OF METAL IONSP41RR001395 · NCRR · MARINE BIOLOGICAL LABORATORY · PI SMITH, PETER JS · 1985 to 2010
$12.7M
Insulinotropin: A Modulator Of B-Cell Glucose SignalingR01DK045817 · NIDDK · UPSTATE MEDICAL UNIVERSITY · PI HOLZ, GEORGE G · 2001 to 2008
$3.0M
Molecular Basis of Antidiabetogenic Hormone ActionR01DK069575 · NIDDK · UPSTATE MEDICAL UNIVERSITY · PI HOLZ, GEORGE G · 2007 to 2017
$2.9M
NCRR NIH HHS P41 RR001395NCRR NIH HHS P41-RR-001395NIDDK NIH HHS R01 DK045817NIDDK NIH HHS R01-DK-04817NIDDK NIH HHS R01 DK069575NIDDK NIH HHS R01-DK-069575
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calcium SignalingComputer SimulationModels, Biological3',5'-Cyclic-AMP PhosphodiesterasesAdenylyl CyclasesAnimalsCalmodulinCyclic AMPGlucagon-Like Peptide-1 ReceptorGlucoseHumansInsulinInsulin-Secreting CellsInsulin SecretionKATP ChannelsReceptors, Glucagon3',5'-Cyclic-AMP PhosphodiesterasesAdenylyl CyclasesCalmodulinCyclic AMPGLP1R protein, humanGlucagon-Like Peptide-1 ReceptorGlucoseInsulinKATP ChannelsReceptors, Glucagon

Identifiers

PMID17989206
PMCPMC3501003
OpenAlexW2113763892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.