ReviewJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2008
Metals in the "omics" world: copper homeostasis and cytochrome c oxidase assembly in a new light.
Review in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Clinical translation and landscape of copper nanoparticles.Drug delivery and translational research · 2026Review
- Oxidative stress and cardiovascular risk related to urinary metal(loid) levels in a pediatric population.Environmental geochemistry and health · 2026Article
- Activation of zinc uptake regulator by zinc binding to three regulatory sites.Nucleic acids research · 2024Article
- A gold speciation that adds a second layer to synergistic gold-copper toxicity inApplied and environmental microbiology · 2024Article
- A Critical Review on the Recovery of Base and Critical Elements from Electronic Waste-Contaminated Streams Using Microbial Biotechnology.Applied biochemistry and biotechnology · 2023Review
- Substrate Induced Movement of the Metal Cofactor between Active and Resting State.Angewandte Chemie (International ed. in English) · 2022Article
- Association of Oxidative Stress with Neurological Disorders.Current neuropharmacology · 2022Article
- MtCOPT2 is a CuMycorrhiza · 2020Article
- Redox balance and DNA fragmentation in arsenic-exposed occupational workers from different industries of Pakistan.Environmental science and pollution research international · 2018Article
- Relationship between Metal Pollution and Gene Expression of Insulin-like Growth Factor II.Journal of health & pollution · 2018Article
- Antioxidant enzymes status and reproductive health of adult male workers exposed to brick kiln pollutants in Pakistan.Environmental science and pollution research international · 2016Article
- Copper Homeostasis for the Developmental Progression of Intraerythrocytic Malarial Parasite.Current topics in medicinal chemistry · 2016Review
- Heavy metals and epigenetic alterations in brain tumors.Current genomics · 2014Article
- Oxidative stress in neurodegenerative diseases.Neural regeneration research · 2012Review
- Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy.Genome research · 2011Article
- Metalloproteomics: forward and reverse approaches in metalloprotein structural and functional characterization.Current opinion in chemical biology · 2011Review
- A novel heme a insertion factor gene cotranscribes with the Thermus thermophilus cytochrome ba3 oxidase locus.Journal of bacteriology · 2010Article
- Suppression mechanisms of COX assembly defects in yeast and human: insights into the COX assembly process.Biochimica et biophysica acta · 2009Review
- How do bacterial cells ensure that metalloproteins get the correct metal?Nature reviews. Microbiology · 2009Review
- Metal ions in biological catalysis: from enzyme databases to general principles.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2008Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
System-level understanding of living organisms has been a long-standing goal of biological sciences. However, it was only recently that this possibility became concrete, by virtue of the development of technology platforms for the production of "omics" data from multiple experimental sources. Data sets such as those from genomics and proteomics are endowing researchers with an unprecedented view of the molecular constituents of cells and of their interactions, forming the basis to pursue the comprehension of how the concerted action of such components can determine biological functions. Within this challenge, bioinorganic chemistry is invested with a renewed significance, being called to place its distinctive subject matter, namely, the study of the interactions between inorganic and biological molecules, in a system-wide perspective. The first step to take in this direction is the construction of "omics" data sets for metalloproteins (metalloproteomics) that can be fruitfully integrated with other protein-centered "omics" data. While looking forward to the progress of high-throughput experimental techniques to accomplish this task, theoretical methods are yielding valuable predictions as to the number of metalloproteins encoded in various genomes. The integrated use of these and others "omics" data can be extremely useful to model complex cellular processes involving metals. Here, we review the current knowledge on copper homeostasis and the assembly of cytochrome c oxidase to exemplify the kind of important processes which need to be studied at the system level. The long-term goal of this approach is the overall description of how metals are framed as essential factors within living cells, which in fact is the ultimate purpose of bioinorganic chemistry.
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