ReviewBMC systems biology2007
Models for synthetic biology.
Review in BMC systems biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- How to Build a Biological Machine Using Engineering Materials and Methods.Biomimetics (Basel, Switzerland) · 2020Article
- Construction of hybrid regulated mother-specific yeast promoters for inducible differential gene expression.PloS one · 2018Article
- Chemical master equation closure for computer-aided synthetic biology.Methods in molecular biology (Clifton, N.J.) · 2015Article
- Investigation of Changes in Tetracycline Repressor Binding upon Mutations in the Tetracycline Operator.Journal of chemical and engineering data · 2014Article
- Solution of Chemical Master Equations for Nonlinear Stochastic Reaction Networks.Current opinion in chemical engineering · 2014Article
- Engineered temperature compensation in a synthetic genetic clock.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- A computational pipeline for identifying kinetic motifs to aid in the design and improvement of synthetic gene circuits.BMC bioinformatics · 2013Article
- A tissue-engineered jellyfish with biomimetic propulsion.Nature biotechnology · 2012Article
- Stochastic simulations of a synthetic bacteria-yeast ecosystem.BMC systems biology · 2012Article
- Derivation, identification and validation of a computational model of a novel synthetic regulatory network in yeast.Journal of mathematical biology · 2011Article
- Analytical Derivation of Moment Equations in Stochastic Chemical Kinetics.Chemical engineering science · 2011Article
- Stochastic simulations of the tetracycline operon.BMC systems biology · 2011Article
- SynBioSS-aided design of synthetic biological constructs.Methods in enzymology · 2011Article
- Positive autoregulation shapes response timing and intensity in two-component signal transduction systems.Journal of molecular biology · 2010Article
- Programming cells: towards an automated 'Genetic Compiler'.Current opinion in biotechnology · 2010Review
- SynBioSS designer: a web-based tool for the automated generation of kinetic models for synthetic biological constructs.Briefings in bioinformatics · 2010Article
- Function and specificity of synthetic Hox transcription factors in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Classification of genes and putative biomarker identification using distribution metrics on expression profiles.PloS one · 2010Article
- Mathematical modeling: bridging the gap between concept and realization in synthetic biology.Journal of biomedicine & biotechnology · 2010Review
- Robust synthetic biology design: stochastic game theory approach.Bioinformatics (Oxford, England) · 2009Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior. The objective is the design and construction of new biological devices and systems to deliver useful applications. Numerous synthetic gene circuits have been created in the past decade, including bistable switches, oscillators, and logic gates, and possible applications abound, including biofuels, detectors for biochemical and chemical weapons, disease diagnosis, and gene therapies. More than fifty years after the discovery of the molecular structure of DNA, molecular biology is mature enough for real quantification that is useful for biological engineering applications, similar to the revolution in modeling in chemistry in the 1950s. With the excitement that synthetic biology is generating, the engineering and biological science communities appear remarkably willing to cross disciplinary boundaries toward a common goal.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.