Trial reportBMC cardiovascular disorders2007
Effect of "no added salt diet" on blood pressure control and 24 hour urinary sodium excretion in mild to moderate hypertension.
Trial report in BMC cardiovascular disorders, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00491881 (Effect of "no Added Salt Diet " on Blood Pressure Control & 24 Hour Urinary Sodium Excretion in Mild to Moderate Hypertension), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of "no Added Salt Diet " on Blood Pressure Control & 24 Hour Urinary Sodium Excretion in Mild to Moderate Hypertension
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Effect of longer-term modest salt reduction on blood pressure.The Cochrane database of systematic reviews · 2013Pooled it
- Veterans service organization engagement in 'POWER,' a peer-led hypertension intervention.Chronic illness · 2012Trial
- Sodium Chloride in Food.Foods (Basel, Switzerland) · 2025Review
- Article
- Prevalence, awareness, treatment and control of hypertension and sodium intake in Jiangsu Province, China: a baseline study in 2014.BMC public health · 2016Article
- The Comparison of Dietary Behaviors among Rural Controlled and Uncontrolled Hypertensive Patients.Advances in preventive medicine · 2016Article
- Role of dietary salt and potassium intake in cardiovascular health and disease: a review of the evidence.Mayo Clinic proceedings · 2013Review
- High-salt diet and hypertension: focus on the renin-angiotensin system.Kidney & blood pressure research · 2011Review
- Correlates of self-care behaviors for managing hypertension among Korean Americans: a questionnaire survey.International journal of nursing studies · 2010Article
- Hypertension in athletes.Journal of clinical hypertension (Greenwich, Conn.) · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of Hypertension as a major cardiovascular threat is increasing. The best known diet for hypertensives is 'no added salt diet'. In this study we evaluated the effect of 'no added salt diet' on a hypertensive population with high dietary sodium intake by measuring 24 hour urinary sodium excretion.
methodsIn this single center randomized study 80 patients (60 cases and 20 controls) not on any drug therapy for hypertension with mild to moderate hypertension were enrolled. 24 hour holter monitoring of BP and 24 hour urinary sodium excretion were measured before and after 6 weeks of 'no added salt diet'.
resultsThere was no statistically significant difference between age, weight, sex, Hyperlipidemia, family history of hypertension, mean systolic and diastolic BP during the day and at night and mean urinary sodium excretion in 24 hour urine of case and control groups. Seventy eight percent of all patients had moderate to high salt intake. After 6 week of 'no added salt diet' systolic and diastolic BP significantly decreased during the day (mean decrease: 12.1/6.8 mmhg) and at night (mean decrease: 11.1/5.9 mmhg) which is statistically significant in comparison to control group (P 0.001 and 0.01). Urinary sodium excretion of 24 hour urine decreased by 37.1 meq/d +/- 39,67 mg/dl in case group which is statistically significant in comparison to control group (p: 0.001). Only 36% of the patients, after no added salt diet, reached the pretreatment goal of 24 hour urinary sodium excretion of below 100 meq/dl (P:0.001).
conclusionDespite modest effect on dietary sodium restriction, no added salt diet significantly decreased systolic and diastolic BP and so it should be advised to every hypertensive patient.
trial registrationClinicaltrial.govnumber NCT00491881.
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