ArticleJournal of neurochemistry2008
Crustacean dopamine receptors: localization and G protein coupling in the stomatogastric ganglion.
Article in Journal of neurochemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Analysis of adaptive molecular mechanisms in response to low salinity in antennal gland of mud crab,Heliyon · 2024Article
- Motor neurons within a network use cell-type specific feedback mechanisms to constrain relationships among ion channel mRNAs.Journal of neurophysiology · 2023Article
- Regulation ofiScience · 2022Article
- The dynamic range of voltage-dependent gap junction signaling is maintained byJournal of neurophysiology · 2022Article
- Modulator-Gated, SUMOylation-Mediated, Activity-Dependent Regulation of Ionic Current Densities Contributes to Short-Term Activity Homeostasis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Activation mechanism of a neuromodulator-gated pacemaker ionic current.Journal of neurophysiology · 2017Article
- Deep sequencing of transcriptomes from the nervous systems of two decapod crustaceans to characterize genes important for neural circuit function and modulation.BMC genomics · 2016Article
- Biochemical characteristics and modulation by external and internal factors of aminopeptidase-N activity in the hepatopancreas of a euryhaline burrowing crab.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2015Article
- Neuropeptide receptor transcript expression levels and magnitude of ionic current responses show cell type-specific differences in a small motor circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Monoaminergic tone supports conductance correlations and stabilizes activity features in pattern generating neurons of the lobster, Panulirus interruptus.Frontiers in neural circuits · 2015Article
- Article
- D1-like dopamine receptors downregulate Na+-K+-ATPase activity and increase cAMP production in the posterior gills of the blue crab Callinectes sapidus.American journal of physiology. Regulatory, integrative and comparative physiology · 2014Article
- Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR.BMC neuroscience · 2013Article
- Review
- Tonic dopamine induces persistent changes in the transient potassium current through translational regulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Dopamine-induced oscillations of the pyloric pacemaker neuron rely on release of calcium from intracellular stores.Journal of neurophysiology · 2011Article
- Amphioxus expresses both vertebrate-type and invertebrate-type dopamine D(1) receptors.Invertebrate neuroscience : IN · 2010Article
- Cell specific dopamine modulation of the transient potassium current in the pyloric network by the canonical D1 receptor signal transduction cascade.Journal of neurophysiology · 2010Article
- Dopamine modulates Ih in a motor axon.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- D(2) receptors receive paracrine neurotransmission and are consistently targeted to a subset of synaptic structures in an identified neuron of the crustacean stomatogastric nervous system.The Journal of comparative neurology · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Neuromodulators, such as dopamine (DA), control motor activity in many systems. To begin to understand how DA modulates motor behaviors, we study a well-defined model: the crustacean stomatogastric nervous system (STNS). The spiny lobster STNS receives both neuromodulatory and neurohormonal dopaminergic input, and extensive background information exists on the cellular and network effects of DA. However, there is a void of information concerning the mechanisms of DA signal transduction in this system. In this study, we show that Gs, Gi, and Gq are activated in response to DA in STNS membrane preparations from five crustacean species representing distant clades in the order Decapoda. Three evolutionarily conserved DA receptors mediate this response in spiny lobsters: D(1alphaPan), D(1betaPan) and D(2alphaPan). G protein coupling for these receptors can vary with the cell type. In the native membrane, the D(1alphaPan) receptor couples with Gs and Gq, the D(1betaPan) receptor couples with Gs, and the D(2alphaPan) receptor couples with Gi. All three receptors are localized exclusively to the synaptic neuropil and most likely generate global biochemical signals that alter ion channels in distant compartments, as well as local signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.