Evidence map›Paper›PMID 17985236›Full record

ReviewNeurochemical research2008

Priming in oxytocin cells and in gonadotrophs.

Gareth Leng, Celine Caquineau, Mike Ludwig

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Article
  3. Oxytocin Regulates Stress-Induced Crf Gene Transcription through CREB-Regulated Transcription Coactivator 3.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. A Precision Medicine Approach to Oxytocin Trials.Current topics in behavioral neurosciences
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gareth LengCentre for Integrative Physiology, University of Edinburgh, Edinburgh, EH8 9XD, UK. Gareth.leng@ed.ac.uk
Celine Caquineau
Mike Ludwig

Funding

Biotechnology and Biological Sciences Research Council BB/E015123/1
6 · The paper itself

Abstract

At proestrous, the sensitivity of gonadotrophs to gonadotrophin-releasing hormone (GnRH) increases with repeated exposure to GnRH, a process known as self-priming. An apparently similar phenomenon can also occur in peptidergic neurons; activity-dependent oxytocin release from dendrites can be potentiated by oxytocin itself. In the brain, such priming actions have the potential to alter the strength of communication between neuronal populations for a very prolonged period. In the case of both oxytocin neurons and gonadotrophs, priming appears to involve an augmentation of a readily releasable pool of vesicles.

Indexed as

AnimalsFemaleGonadotropinsHumansMilk EjectionNeuronsOxytocinGonadotropinsOxytocin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.