Trial reportEuropean journal of epidemiology2008
Inflammation a possible link between economical stress and coronary heart disease.
Trial report in European journal of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Financial strain and ideal cardiovascular health in middle-aged and older women: Data from the Women's health study.American heart journal · 2019Trial
- Physiological and Psychological Effects of a Walk in Urban Parks in Fall.International journal of environmental research and public health · 2015Trial
- Elucidation of a physiological adjustment effect in a forest environment: a pilot study.International journal of environmental research and public health · 2015Trial
- Income and recurrent events after a coronary event in women.European journal of epidemiology · 2008Trial
- Optimism, Lifetime Financial Stressors, and Mental Health Among Racially, Sexually, and Gender Minoritized Emerging Adults.Journal of racial and ethnic health disparities · 2026Article
- Facing stress and inflammation: From the cell to the planet.World journal of experimental medicine · 2024Review
- Propensity score weighted associations between financial strain and subsequent inflammatory biomarkers of aging among a representative sample of U.S. older adults.BMC geriatrics · 2022Article
- Leveraging naturally occurring variation in financial stress to examine associations with inflammatory burden among older adults.Journal of epidemiology and community health · 2020Article
- Food Insecurity and Odds of High Allostatic Load in Puerto Rican Adults: The Role of Participation in the Supplemental Nutrition Assistance Program During 5 Years of Follow-Up.Psychosomatic medicine · 2018Article
- Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society.Scientific reports · 2017Article
- Beyond obesity and lifestyle: a review of 21st century chronic disease determinants.BioMed research international · 2014Review
- Observational study of 1-year mortality rates before and after a major earthquake among Chinese nonagenarians.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011Article
- The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design.European journal of epidemiology · 2010Article
- New studies, technology, and the progress of epidemiology.European journal of epidemiology · 2010Article
- The Generation R Study: design and cohort update 2010.European journal of epidemiology · 2010Article
- Early influences on cardiovascular and renal development.European journal of epidemiology · 2010Review
- The Rotterdam Study: 2010 objectives and design update.European journal of epidemiology · 2009Article
- Recent trends in cardiovascular epidemiology.European journal of epidemiology · 2009Article
- Community-dwelling older adults who are low-income and disabled weathering financial challenges.Geriatric nursing (New York, N.Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the relationship between economical stress, as an indicator of SES, and inflammation in women patients with coronary heart disease (CHD).
designa cross-sectional study. SETTING AND
participantsTwo hundred and thirteen women patients recruited from two hospitals in Stockholm, Sweden; mean age 63+/-8, range 35-75 years, hospitalised for acute myocardial infarction, coronary angioplasty or bypass surgery between 1996 and 2000, examined in a stable phase, 1 year and 5 months (+/-2.5 months) after the index event.
main outcome measuresEconomical stress, and other SES indicators were assessed by questionnaires. Levels of high-sensitivity C-reactive protein (CRP) were measured by nephelometry and the concentrations of interleukin-6 (Il-6) and interleukin-1 receptor antagonist (Il-1ra) were determined by enzyme-linked immunoassay.
resultsAfter controlling for the potential confounders, i.e. treatment, menstruational, marital and education status in addition to age, patients having economical stress showed higher levels of hsCRP (2.79 vs. 1.83 mg/l, p=0.04), Il-6 (3.12 vs. 2.38 mg/l, p=0.015) and Il-1ra (599 vs. 456 mg/l, p=0.02). The association persisted after controlling for other measures of economical status, like personal and household income. According to our mediational analyses, lifestyle variables, especially BMI, could partly explain the observed association.
conclusionHigh economical stress was associated with higher Il-6, CRP and Il-1ra levels in women with stable CHD. The direction of causality cannot be inferred from such a cross-sectional study however, our results raise the possibility that increased inflammatory activity is a mediator for the effect of economical stress on adverse outcomes after a coronary event.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.