Evidence map›Paper›PMID 17984995›Full record

ReviewGene therapy2007

Progress and prospects: gene therapy clinical trials (part 2).

Eric Alton, Stefano Ferrari, Uta Griesenbach, A Aiuti, A C Bachoud-Lévi, A Blesch, M K Brenner, F Cattaneo, E A Chiocca, G Gao and 11 more

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Gene therapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Oncolytic Virotherapy in Solid Tumors: A Current Review.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  2. Article
  3. Scaling genetic resources: New paradigms for diagnosis and treatment of rare genetic disease.American journal of medical genetics. Part C, Seminars in medical genetics · 2023
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. [Research advances on gene therapy for hemophilia A].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2015
    Article
  11. Efficient in vitro gene delivery by hybrid biopolymer/virus nanobiovectors.Journal of controlled release : official journal of the Controlled Release Society · 2014
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Gene and cell therapy based treatment strategies for inflammatory bowel diseases.World journal of gastrointestinal pathophysiology · 2011
    Article
  17. Article
  18. Review
  19. Article
  20. Selective gene transfection of individual cells in vitro with plasmonic nanobubbles.Journal of controlled release : official journal of the Controlled Release Society · 2011
    Article
4 · The record

Corrections and comments

  • Erratum issued
    Alton, Eric [removed]; Ferrari, Stefano [removed]; Griesenbach, Uta [removed]; Aiuti, A [added]; Bachoud-Lévi, A C [added]; Blesch, A [added]; Brenner, M K [added]; Cattaneo, F [added]; Chiocca, E A [added]; Gao, G [added]; High, K A [added]; Leen, A M [a
5 · Who and what money

Authors and funding

21 authors.

Eric AltonDepartment of Gene Therapy, Emmanuel kaye Building, NHLI, Imperial College, Manresa Road, London, UK.
Stefano Ferrari
Uta Griesenbach
A Aiuti
A C Bachoud-Lévi
A Blesch
M K Brenner
F Cattaneo
E A Chiocca
G Gao
K A High
A M Leen
N R Lemoine
I A McNeish
G Meneguzzi
M Peschanski
M G Roncarolo
D S Strayer
M H Tuszynski
D J Waxman
J M Wilson

Funding

Telethon TGT06F01Telethon TGT06S01
6 · The paper itself

Abstract

This is the second part of a review summarizing progress and prospects in gene therapy clinical research. Twenty key diseases/strategies are succinctly described and commented on by leaders in the field. This part includes clinical trials for skin diseases, neurological disorders, HIV/AIDS, ornithine transcarbamylase deficiency, alpha(1)-antitrypsin deficiency, haemophilia and cancer.

Indexed as

Clinical Trials as TopicGenetic TherapyGenetic VectorsGene Transfer TechniquesHumansNeoplasmsStem Cell Transplantation

Identifiers

PMID17984995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.