Trial reportThe American journal of tropical medicine and hygiene2007
A cluster-randomized bovine intervention trial against Schistosoma japonicum in the People's Republic of China: design and baseline results.
Trial report in The American journal of tropical medicine and hygiene, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of preventive health educational videos targeting infectious diseases in schoolchildren.The American journal of tropical medicine and hygiene · 2012Pooled it
- A cluster-randomised intervention trial against Schistosoma japonicum in the Peoples' Republic of China: bovine and human transmission.PloS one · 2009Trial
- Transmission-Blocking Vaccines against Schistosomiasis Japonica.International journal of molecular sciences · 2024Review
- Predictors of bovine Schistosoma japonicum infection in rural Sichuan, China.International journal for parasitology · 2022Article
- Review
- Process Development of Sj-p80: A Low-Cost Transmission-Blocking Veterinary Vaccine for Asiatic Schistosomiasis.Frontiers in immunology · 2020Article
- Field Evaluation of Recombinant Antigen ELISA in Detecting Zoonotic Schistosome Infection Among Water Buffaloes in Endemic Municipalities in the Philippines.Frontiers in veterinary science · 2020Article
- The contribution of domestic animals to the transmission of schistosomiasis japonica in the Lindu Subdistrict of the Central Sulawesi Province, Indonesia.Veterinary world · 2019Article
- Schistosomiasis Elimination: Beginning of the End or a Continued March on a Trodden Path.Tropical medicine and infectious disease · 2019Article
- Asian Schistosomiasis: Current Status and Prospects for Control Leading to Elimination.Tropical medicine and infectious disease · 2019Review
- Schistosome Vaccines for Domestic Animals.Tropical medicine and infectious disease · 2018Review
- Real-time PCR diagnosis of Schistosoma japonicum in low transmission areas of China.Infectious diseases of poverty · 2018Article
- Geographic strain differentiation of Schistosoma japonicum in the Philippines using microsatellite markers.PLoS neglected tropical diseases · 2017Article
- Exposure to cows is not associated with diarrhoea or impaired child growth in rural Odisha, India: a cohort study.Epidemiology and infection · 2016Article
- Development and optimization of cocktail-ELISA for a unified surveillance of zoonotic schistosomiasis in multiple host species.Parasitology research · 2015Article
- High prevalence of Schistosoma japonicum and Fasciola gigantica in bovines from Northern Samar, the Philippines.PLoS neglected tropical diseases · 2015Article
- Spatial analysis of Schistosomiasis in Hubei Province, China: a GIS-based analysis of Schistosomiasis from 2009 to 2013.PloS one · 2015Article
- Real-time PCR demonstrates high prevalence of Schistosoma japonicum in the Philippines: implications for surveillance and control.PLoS neglected tropical diseases · 2015Article
- Local immune responses of the Chinese water buffalo, Bubalus bubalis, against Schistosoma japonicum larvae: crucial insights for vaccine design.PLoS neglected tropical diseases · 2013Article
- Surveillance of Schistosoma japonicum infection in domestic ruminants in the Dongting Lake region, Hunan province, China.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
We describe the design and report baseline results of a cluster-randomized intervention to determine the importance of bovines for Schistosoma japonicum transmission in southern China. The study involves four matched village pairs in Hunan and Jiangxi Provinces, with a village within each pair randomly selected as intervention (human and bovine praziquantel treatment) or control (human praziquantel treatment only). Total study population prevalences at baseline were 12.4% (n = 5,390) and 15.2% (n = 1,573) for humans and bovines, respectively; village prevalences were similar within pairs. Bovine contamination index calculations showed that bovines less than 24 months of age were responsible for 74% of daily bovine environmental contamination with S. japonicum eggs. The village characteristics and baseline results underpin a rigorous study, which has major implications for deployment of a transmission-blocking bovine vaccine against S. japonicum. The combination of such a vaccine with other control strategies could potentially eliminate S. japonicum from southern China.
Indexed as
Identifiers
17984344PMC2756501What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.