ArticleNucleic acids research2008
EPGD: a comprehensive web resource for integrating and displaying eukaryotic paralog/paralogon information.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- pATsi: Paralogs and Singleton Genes from Arabidopsis thaliana.Evolutionary bioinformatics online · 2016Review
- An easy-to-use primer design tool to address paralogous loci and T-DNA insertion sites in the genome of Arabidopsis thaliana.Plant methods · 2014Article
- A novel approach for protein subcellular location prediction using amino acid exposure.BMC bioinformatics · 2013Article
- Duplication and maintenance of the Myb genes of vertebrate animals.Biology open · 2013Article
- Transcriptome analysis reveals the time of the fourth round of genome duplication in common carp (Cyprinus carpio).BMC genomics · 2012Article
- Molecular phylogeny and functional genomics of beta-galactoside alpha2,6-sialyltransferases that explain ubiquitous expression of st6gal1 gene in amniotes.The Journal of biological chemistry · 2010Article
- Comparing the retention mechanisms of tandem duplicates and retrogenes in human and mouse genomes.Genetics, selection, evolution : GSE · 2010Article
- Accurate distinction of pathogenic from benign CNVs in mental retardation.PLoS computational biology · 2010Article
- Robustness of transcriptional regulatory program influences gene expression variability.BMC genomics · 2009Article
- CHSMiner: a GUI tool to identify chromosomal homologous segments.Algorithms for molecular biology : AMB · 2009Article
- SysZNF: the C2H2 zinc finger gene database.Nucleic acids research · 2009Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene duplication is common in all three domains of life, especially in eukaryotic genomes. The duplicates provide new material for the action of evolutionary forces such as selection or genetic drift. Here we describe a sophisticated procedure to extract duplicated genes (paralogs) from 26 available eukaryotic genomes, to pre-calculate several evolutionary indexes (evolutionary rate, synonymous distance/clock, transition redundant exchange clock, etc.) based on the paralog family, and to identify block or segmental duplications (paralogons). We also constructed an internet-accessible Eukaryotic Paralog Group Database (EPGD; http://epgd.biosino.org/EPGD/). The database is gene-centered and organized by paralog family. It focuses on paralogs and evolutionary duplication events. The paralog families and paralogons can be searched by text or sequence, and are downloadable from the website as plain text files. The database will be very useful for both experimentalists and bioinformaticians interested in the study of duplication events or paralog families.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.