Evidence map›Paper›PMID 17982237›Full record

Trial reportJournal of Korean medical science2007

Treatment of facial seborrheic dermatitis with pimecrolimus cream 1%: an open-label clinical study in Korean patients.

Byung-Soo Kim, Su-Han Kim, Moon-Bum Kim, Chang-Keun Oh, Ho-Sun Jang, Kyung-Sool Kwon

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of Korean medical science, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Seborrheic Dermatitis: Exploring the Complex Interplay withInternational journal of molecular sciences · 2025
    Review
  3. Seborrheic Dermatitis and Dandruff: A Comprehensive Review.Journal of clinical and investigative dermatology · 2015
    Article
  4. Article
  5. Article
  6. Adult seborrheic dermatitis: a status report on practical topical management.The Journal of clinical and aesthetic dermatology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Byung-Soo KimDepartment of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.
Su-Han Kim
Moon-Bum Kim
Chang-Keun Oh
Ho-Sun Jang
Kyung-Sool Kwon
Pusan National University · KRBusan Presbyterian University · KRKyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pimecrolimus cream 1% has shown to be effective in patients with a variety of inflammatory cutaneous disorders. And it might be a useful modality in the treatment of seborrheic dermatitis. This prospective study was aimed at assessing the efficacy and tolerability of pimecrolimus cream 1% in the treatment of facial seborrheic dermatitis. Twenty patients were instructed to apply pimecrolimus cream 1% for 4 consecutive weeks. Assessment of the disease severity was performed at baseline and at week 1, 2, and 4. Clinical assessments of erythema, scaling, and pruritus were measured using a 4-point scale (0-3). Global assessments of the disease severity by patients and investigators were performed at each visit. Mean clinical scores of erythema, scaling, and pruritus significantly improved by 87.4%, 91.9%, and 91.5% respectively at week 4 (p<0.001). Improvements in the global assessment of disease severity determined by patients and investigators also showed excellent results. No specific adverse events other than transient burning and tingling sensations were noted. The relapse of facial seborrheic dermatitis was mostly observed between 3 to 8 weeks after the discontinuation of pimecrolimus. We suggest that the topical application of pimecrolimus cream 1% can be an effective and safe alternative for treatment of facial seborrheic dermatitis.

Indexed as

AdultAgedDermatitis, SeborrheicErythemaFaceFemaleFollow-Up StudiesHumansKoreaMaleMiddle AgedSeverity of Illness IndexTacrolimusTime FactorsTreatment OutcomepimecrolimusTacrolimus

Identifiers

PMID17982237
PMCPMC2693855
OpenAlexW2020836991

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.