ArticleJournal of bacteriology2008
Dam methyltransferase is required for stable lysogeny of the Shiga toxin (Stx2)-encoding bacteriophage 933W of enterohemorrhagic Escherichia coli O157:H7.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Characteristics of Shiga Toxin-ProducingToxins · 2023Article
- Bacterial DNA methyltransferase: A key to the epigenetic world with lessons learned from proteobacteria.Frontiers in microbiology · 2023Review
- Integration of themBio · 2022Article
- Alternating lysis and lysogeny is a winning strategy in bacteriophages due to Parrondo's paradox.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Cytotoxic Effects of Recombinant StxA2-His in the Absence of Its Corresponding B-Subunit.Toxins · 2021Article
- Two Lineages of Pseudomonas aeruginosa Filamentous Phages: Structural Uniformity over Integration Preferences.Genome biology and evolution · 2020Article
- The bacterial epigenome.Nature reviews. Microbiology · 2020Review
- A role for the bacterial GATC methylome in antibiotic stress survival.Nature genetics · 2016Article
- Novel Methyltransferase Recognition Motif Identified in Chania multitudinisentens RB-25(T) gen. nov., sp. nov.Frontiers in microbiology · 2016Article
- Escherichia coli O157:H7 strains harbor at least three distinct sequence types of Shiga toxin 2a-converting phages.BMC genomics · 2015Article
- DNA Methylation.EcoSal Plus · 2014Article
- Comparative genomics of enterohemorrhagic Escherichia coli O145:H28 demonstrates a common evolutionary lineage with Escherichia coli O157:H7.BMC genomics · 2014Article
- The methylome of the gut microbiome: disparate Dam methylation patterns in intestinal Bacteroides dorei.Frontiers in microbiology · 2014Article
- High incidence of multiple antibiotic resistant cells in cultures of in enterohemorrhagic Escherichia coli O157:H7.Mutation research · 2014Article
- Bacteriophage orphan DNA methyltransferases: insights from their bacterial origin, function, and occurrence.Applied and environmental microbiology · 2013Review
- Genes from the exo-xis region of λ and Shiga toxin-converting bacteriophages influence lysogenization and prophage induction.Archives of microbiology · 2013Article
- Genome signature-based dissection of human gut metagenomes to extract subliminal viral sequences.Nature communications · 2013Article
- Identification of genes expressed in cultures of E. coli lysogens carrying the Shiga toxin-encoding prophage Φ24B.BMC microbiology · 2012Article
- Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease.Microbial pathogenesis · 2011Article
- Wolbachia prophage DNA adenine methyltransferase genes in different Drosophila-Wolbachia associations.PloS one · 2011Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Shiga toxin 2 (Stx2), one of the principal virulence factors of enterohemorrhagic Escherichia coli, is encoded by 933W, a lambda-like prophage. 933W prophage induction contributes to Stx2 production, and here, we provide evidence that Dam methyltransferase is essential for maintenance of 933W lysogeny. Our findings are consistent with the idea that the 933W prophage has a relatively low threshold for induction, which may promote Stx2 production during infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.