Evidence map›Paper›PMID 17980525›Full record

ReviewHearing research2008

Purinergic signaling in the inner ear.

Jun Ho Lee, Daniel C Marcus

Open access · greenAbstract readReview
In one paragraph

Review in Hearing research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. βScientific reports · 2017
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Ion homeostasis in the ear: mechanisms, maladies, and management.Current opinion in otolaryngology & head and neck surgery · 2010
    Review
  10. Article
  11. Article
  12. P2Y4-mediated regulation of Na+ absorption in the Reissner's membrane of the cochlea.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010
    Article
  13. Article
  14. Article
  15. Adenosine and the auditory system.Current neuropharmacology · 2009
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 4 countries.

Jun Ho LeeDepartment of Otorhinolaryngology, Seoul National University College of Medicine, Chongro-gu, Seoul 110-744, Republic of Korea. junlee@snu.ac.kr
Daniel C Marcus
Kansas State University · USNew Generation University College · ET

Funding

COCHLEAR AND VESTIBULAR ION TRANSPORTR01DC000212 · NIDCD · KANSAS STATE UNIVERSITY · PI MARCUS, DANIEL C · 1988 to 2009
$3.1M
NIDCD NIH HHS R01 DC000212NIDCD NIH HHS R01-DC00212
6 · The paper itself

Abstract

Epithelial cells of the inner ear coordinate their ion transport activity through a number of mechanisms. One important mechanism is the autocrine and paracrine signaling among neighboring cells in the ear via nucleotides, such as adenosine, ATP and UTP. This review summarizes observations on the release, detection and degradation of nucleotides by epithelial cells of the inner ear. Purinergic signaling is thought to be important for endolymph ion homeostasis and for protection from acoustic over-stimulation.

Indexed as

Signal TransductionAcoustic StimulationAnimalsAuditory PathwaysEar, InnerEndolymphEpithelial CellsHumansHydrolysisMechanotransduction, CellularNoisePurine NucleotidesReceptors, PurinergicReceptors, Purinergic P1Receptors, Purinergic P2Purine NucleotidesReceptors, PurinergicReceptors, Purinergic P1Receptors, Purinergic P2

Identifiers

PMID17980525
PMCPMC2259389
OpenAlexW2068840846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.