Evidence map›Paper›PMID 17979877›Full record

ReviewJournal of cellular and molecular medicine

Calcium-associated mechanisms in gut pacemaker activity.

Shinsuke Nakayama, Shunichi Kajioka, Kazunori Goto, Miyako Takaki, Hong-Nian Liu

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. A Pipeline for the Registration of Calcium Transient Data to Structural Networks of the Interstitial Cells of Cajal.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019
    Article
  3. Article
  4. Article
  5. Control of urinary drainage and voiding.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Review
  6. Article
  7. Article
  8. Orexins stimulate the 'appetite' of the gut.The Journal of physiology · 2011
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Shinsuke NakayamaDepartment of Cell Physiology, Nagoya University Graduate School of Medicine, Nagoya, Japan. h44673a@nucc.cc.nagoya-u.ac.jp
Shunichi Kajioka
Kazunori Goto
Miyako Takaki
Hong-Nian Liu
Nagoya University · JPKyoto University · JPNara Medical University · JPUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A considerable body of evidence has revealed that interstitial cells of Cajal (ICC), identified with c-Kit-immunoreactivity, act as gut pacemaker cells, with spontaneous Ca(2+) activity in ICC as the probable primary mechanism. Namely, intracellular (cytosolic) Ca(2+) oscillations in ICC periodically activate plasmalemmal Ca(2+)-dependent ion channels and thereby generate pacemaker potentials. This review will, thus, focus on Ca(2+)-associated mechanisms in ICC in the gastrointestinal (GI) tract, including auxiliary organs.

Indexed as

AnimalsBiological ClocksCalciumCalcium ChannelsCalcium SignalingChloride ChannelsGastrointestinal TractHumansCalciumCalcium ChannelsChloride Channels

Identifiers

PMID17979877
PMCPMC4401267
OpenAlexW1992334151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.