ArticleJournal of the American Society for Mass Spectrometry2007
Salt tolerance of desorption electrospray ionization (DESI).
Article in Journal of the American Society for Mass Spectrometry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed.
- Ambient ionization mass spectrometry in brain cancer diagnosis.Journal of mass spectrometry and advances in the clinical lab · 2025Review
- Applications of DESI and DART Mass Spectrometry in Forensic Science.Journal of the American Society for Mass Spectrometry · 2025Review
- Elucidating the Role of Ion Suppression in Secondary Electrospray Ionization.Journal of the American Society for Mass Spectrometry · 2023Article
- Re-Imagining Drug Discovery using Mass Spectrometry.Israel journal of chemistry · 2023Article
- Desorption Electrospray Ionization Mass Spectrometry Assay for Label-Free Characterization of SULT2B1b Enzyme Kinetics.ChemMedChem · 2022Article
- Clinically Viable Assay for Monitoring Uromodulin Glycosylation.Journal of the American Society for Mass Spectrometry · 2021Article
- Imaging of Polar and Nonpolar Lipids Using Desorption Electrospray Ionization/Post-photoionization Mass Spectrometry.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Addition of Serine Enhances Protein Analysis by DESI-MS.Journal of the American Society for Mass Spectrometry · 2019Article
- Comparing the Effects of Additives on Protein Analysis Between Desorption Electrospray (DESI) and Electrospray Ionization (ESI).Journal of the American Society for Mass Spectrometry · 2018Article
- Imaging the Unimaginable: Desorption Electrospray Ionization - Imaging Mass Spectrometry (DESI-IMS) in Natural Product Research.Planta medica · 2018Review
- Direct Analysis of Proteins from Solutions with High Salt Concentration Using Laser Electrospray Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2018Article
- Direct Analysis of Triterpenes from High-Salt Fermented Cucumbers Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI).Journal of the American Society for Mass Spectrometry · 2017Article
- Direct Visualization of Neurotransmitters in Rat Brain Slices by Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI - MS).Journal of the American Society for Mass Spectrometry · 2016Article
- Touch spray mass spectrometry for in situ analysis of complex samples.The Analyst · 2014Article
- Screening of complicated matrixes with paper assisted ultrasonic spray ionization mass spectrometry.Journal of the American Society for Mass Spectrometry · 2014Article
- Direct Mass Spectrometry Analysis of Untreated Samples of Ultralow Amounts Using Extraction Nano-Electrospray.Analytical methods : advancing methods and applications · 2013Article
- Direct detection of pharmaceuticals and personal care products from aqueous samples with thermally-assisted desorption electrospray ionization mass spectrometry.Journal of the American Society for Mass Spectrometry · 2011Article
- Interfacing capillary-based separations to mass spectrometry using desorption electrospray ionization.Analytical chemistry · 2011Article
- Analysis of lipids from crude lung tissue extracts by desorption electrospray ionization mass spectrometry and pattern recognition.Analytical biochemistry · 2011Article
- Enhanced ion signals in desorption electrospray ionization using surfactant spray solutions.Journal of the American Society for Mass Spectrometry · 2010Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The salt tolerance of desorption electrospray ionization (DESI) was systematically investigated by examining three different drug mixtures in the presence of 0, 0.2, 2, 5, 10, and 20% NaCl:KCl (1:1) from different surfaces. At physiological salt concentrations, the individual drugs in each mixture were observed in each experiment. Even at salt concentrations significantly above physiological levels, particular surfaces were effective in providing spectra that allowed the ready identification of the compounds of interest in low nanogram amounts. Salt adducts, which are observed even in the absence of added salt, could be eliminated by adding 0.1% 7 M ammonium acetate to the standard methanol:water (1:1) spray solvent. Comparison of the salt tolerance of DESI with that of electrospray ionization (ESI) demonstrated better signal/noise characteristics for DESI. The already high salt tolerance of DESI can be optimized further by appropriate choices of surface and spray solution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.