Evidence map›Paper›PMID 17973257›Full record

ReviewInternational journal of cancer2008

Recent advances in strategies for immunotherapy of human papillomavirus-induced lesions.

Shreya Kanodia, Diane M Da Silva, W Martin Kast

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal of cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 69 citations in OpenAlex.

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  20. Vaccines to prevent infections by oncoviruses.Annual review of microbiology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shreya KanodiaDepartment of Molecular Microbiology and Immunology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
Diane M Da Silva
W Martin Kast
University of Southern California · US

Funding

Protein Expression and Peptide CoreP01CA097296 · NCI · UNIVERSITY OF CHICAGO · PI SCHREIBER, HANS · 2003 to 2012
$15.0M
VLP VACCINES AGAINST HPV INDUCED TUMORSR01CA074397 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAST, WIJBE MARTIN · 1997 to 2020
$5.5M
Training in Genetic, Molecular and Cellular BiologyT32GM067587 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STALLCUP, MICHAEL R · 2003 to 2012
$1.8M
NCI NIH HHS P01 CA097296NCI NIH HHS P01 CA97296NCI NIH HHS R01 CA074397NCI NIH HHS R01 CA74397NIGMS NIH HHS T32 GM 067587NIGMS NIH HHS T32 GM067587
6 · The paper itself

Abstract

Human papillomavirus (HPV)-induced lesions are distinct in that they have targetable foreign antigens, the expression of which is necessary to maintain the cancerous phenotype. Hence, they pose as a very attractive target for "proof of concept" studies in the development of therapeutic vaccines. This review will focus on the most recent clinical trials for the immunotherapy of mucosal and cutaneous HPV-induced lesions as well as emerging therapeutic strategies that have been tested in preclinical models for HPV-induced lesions. Progress in peptide-based vaccines, DNA-based vaccines, viral/bacterial vector-based vaccines, immune response modifiers, photodynamic therapy and T cell receptor based therapy for HPV will be discussed.

Indexed as

AnimalsClinical Trials as TopicDisease Models, AnimalHumansImmunotherapyPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPhenotypePhotochemotherapyVaccines, DNAPapillomavirus VaccinesVaccines, DNA

Identifiers

PMID17973257
PMCPMC4943456
OpenAlexW1549035661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.